泻心汤配伍沉淀物的药效学研究  

Pharmacodvnamic Study on the Sediments that Produced by Matching of Herbs in Xiexintang

作　　者：李建荣[1] 张广平[1] 吴兰生[1] 严梅桢[1] 宋红月[1] 

机构地区：[1]中国中医研究院中药研究所,北京100700

出　　处：《中国实验方剂学杂志》2004年第5期27-30,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局中医药科学技术研究专项资金(0 2 0 32 957)

摘　　要：目的 :观察泻心汤配伍后产生沉淀物的药效。方法 :在大鼠幽门结扎与阿斯匹林复合溃疡模型、大鼠角叉菜胶气囊法所致炎症模型上比较其煎液、上清液和沉淀物的药效 ;比较三者对金黄色葡萄球菌及大肠杆菌临床分离株的体外抑菌效果。结果 :泻心汤沉淀物的抗溃疡和抗炎作用与其煎液相似。结论Objective: To observe the Pharmacological effect of the sediments produced by matching of Herbs in Xiexintang.Method:Gastric ulcer model of rat induced by polorous ligation with aspirin administration model of rat induced by carragreenin were used.Bactriostatic effect was evaluated by using gold staphylococcus and Escherichia.Effects of Xiexin decoction,the supemate and the sediments of the decoction were compared by using the above mentioned models and bacterial cultuer.Result:The effects of the sediments of Xiexin decoction and that of the Xiexin decoction are similar.Conclusion:Biological activity of the sediments that produced by matching of herbs of Xiexintang decocting and that of the Xiexin decoction are the same.

关 键 词：泻心汤 沉淀物 抗溃疡 抗炎 抗菌 

分 类 号：R285.5[医药卫生—中药学]