超敏促甲状腺激素在糖尿病并发心肌梗死中的作用  

The Effect of Hypersensitive Thyroid Stimulating Hormone in Diabetes Patients with AMI

作　　者：唐浩熙[1] 李介华[1] 夏明凯[1] 张小勇[1] 李绍清[1] 李冬秀[1] 岑欢[1] 

机构地区：[1]暨南大学医学院第五附属医院暨广东省清远市人民医院

出　　处：《中西医结合心脑血管病杂志》2005年第4期306-307,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广东省清远市科技局计划项目 (No .2 0 0 4 1 72 1 )

摘　　要：目的　观察超敏促甲状腺激素(hs -TSH )在糖尿病合并急性心肌梗死(AMI)中的作用 ,预测糖尿病合并AMI。方法　正常对照组 5 0例 ;A组为无合并症糖尿病病人 67例 ;B组为非AMI急性合并症糖尿病病人 5 3例 ;C组为非糖尿病史AMI病人 10 4例 ;D组为糖尿病合并AMI病人 3 2例。检测空腹hs -TSH。结果　A组hs -TSH浓度为 (0 .97± 0 .3 2 )mIU /L ,B组hs -TSH浓度为 (0 .47±0 .19)mIU /L ,C组为 (0 .67± 0 .42 )mIU/L ,D组为 (0 .49± 0 .2 3 )mIU /L。正常对照组为 (2 .95± 0 .2 1)mIU /L。A组与B组比较、C组与D组比较均有统计学意义 ,B组与D组比较无统计学意义。糖尿病合并AMI病人的hs -TSH浓度与非AMI急性合并症比较无统计学意义。结论　糖尿病病人随着血糖的增高hs -TSH下降 ,当产生急性合并症时hs -TSH显著下降 ,hs -TSH可作为预测糖尿病合并AMI的指标。Objective To observe the effect of hs-TSH in diatetes with AMI.Methods Subjects were divided into five groups:50 healthy subjects as control,diabetes without complications as group A(n=67),diabetes without AMI as group B(n=53),AMI without diabetes as group C(n=104),diabetes with AMI as group D(n=32),FBG and hs-TSH were measured in control group,group A and group B.Hs-TSH and cTnI were obtained in group C and group D.Results The serum hs-TSH levels of A,B,C,D and control group were(0.97±0.32),(0.47±0.19),(0.67±0.42),(0.49±0.23),(2.95±0.21)mIU/L,respectively.There was a significant difference between group A and group B,group C and group D,but no significant differenct was found between group B and group D.Conclusion The serum hs-TSH level increased in deatetes,but reduced with complication.It may be a predictive index of diabetes with AMI.

关 键 词：超敏促甲状腺激素 糖尿病 急性心肌梗死 合并症 预测指标 

分 类 号：R542.22[医药卫生—心血管疾病]