广州脐血库3605脐血供者6个月后随访  

Follow-up of 3 605 Cord Blood Donors after 6 Months of Cord Blood Donation in Guangzhou Cord Blood Bank

作　　者：陈劲松[1] 廖灿[1] 黎丽仙[1] 辜少玲[1] 许遵鹏[1] 吴韶清[1] 钟惠珠[1] 

机构地区：[1]广州市妇婴医院广州脐血库,广州510180

出　　处：《中国实验血液学杂志》2005年第2期317-319,共3页Journal of Experimental Hematology

基　　金：广东省科委重点科技攻关课题广东省卫生厅"五个一工程"重大科研项目(穗卫科学1996-23)广州市科委重点课题(96-Z-64-1和99-Z-008-01)广州市卫生局重点攻关项目

摘　　要：本研究回顾分析了脐血库对库存3 605份脐血所进行的脐血供者6个月后的随访情况,探讨供者随访制 度在脐血库运作过程中的作用。1998年6月至2004年2月间,通过电话、信函方式对捐献脐血满6个月的母亲进 行了母婴健康调查随访,对脐血的质量作出了评估。结果表明:有3 195人接受了电话随访,18人婉拒。对于无法 通过电话随访的,则采用信函调查形式,共发信392封,回信15封。电话随访每例平均耗时12分钟。随访资料显 示婴儿染色体异常2例、先天性甲状腺功能低下1例、粒细胞减少症1例、白化病1例、不明原因死亡5例。所有这 些被查明为非正常婴儿供者的脐血均被废弃。总之:脐血库进行脐血供者6个月后的随访工作,能有效地提高库 存脐血的质量。To study the program of evaluating mothers and infants after 6 months of cord blood donation, from June 1998 to Feberary 2004, all mothers after 6 months of cord blood donation were followed-up by phone calls or letters to report on the health condition. The results showed that when 3 195 mothers were visited by phone calls , 18 mothers declined to answer. 392 letter were send to those who could not be found by phone, 15 of whom wrote back. The average time to talk with each mother was approximately 12 minutes. Follow-up on the baby donors showed two cases with chromosome abnormality, one with hypothyroidism, one with neutropenia, one with albinism and 5 dead with unclear reasons. The cord blood components from all these abnormal donors found were discarded. In conclusion, the programs to evaluate mother and baby after 6 months of cord blood donation seems important in quality control of the components stored in cord blood bank.

关 键 词：脐血 供者随访 脐血库 

分 类 号：R457.1[医药卫生—治疗学] R331[医药卫生—临床医学]