第二次全国自身抗体检测的质控总结  

Quality control report for autoantibodies detection of 2003

作　　者：徐幼筠[1] 吴东海[1] 

机构地区：[1]中日友好医院风湿免疫科,北京100029

出　　处：《中华风湿病学杂志》2005年第4期211-214,共4页Chinese Journal of Rheumatology

摘　　要：目的了解我国自身抗体检测的现状,促进自身抗体检测的水平。方法以自愿报名方式确定参与单位。质控项目包括抗核抗体(ANA)、抗双链DNA抗体(抗dsDNA抗体)、抗可提取核抗原(ENA)抗体、抗线粒体抗体(AMA)、抗平滑肌抗体(ASMA)5项,共12份标本。标本发放及结果分析采用双盲操作。结果ANA正确率85.4%;抗dsDNA抗体正确率81.8%;抗ENA抗体正确率36.9%;AMA正确率66.7%、ASMA正确率50%。结论与第一次质控相比,总的来说各项抗体的检测水平有一定提高。Objective To evaluate the current situation of autoantibodies detection in China in order to improve the quality of detection. Method Inviting letters to partitcipate this evaluation were sent to all laboratories that detect auto-antibodies. Those responding laboratories were enrolled to this study. The testing items included antinuclear antibody, anti-dsDNA antibody, anti-ENA antibody, anti-mitochondrial antobody and anti-smooth muscle antibody. The distribution of samples and the analysis of results were both double-blinded. Result The correct rate of ANA, anti-dsDNA antibody, anti-ENA antibody, anti-mitochondria antibody and anti-smooth muscle antibody was 85.4%,81.8%,36.9%, 66.7%, and 50% respectively. Conclusion Comparing with the first quality control results, the overall results is this evaluation have been improved, but there is still a longway to go.

关 键 词：自身抗体检测 质控 抗DSDNA抗体 抗核抗体(ANA) 抗双链DNA抗体 抗可提取核抗原 二次 抗线粒体抗体 抗平滑肌抗体 抗ENA抗体 报名方式 检测水平 AMA 标本 

分 类 号：R593.2[医药卫生—内科学]