急性甲醇中毒性脑病的CT及MR表现  

CT and MR Manifestations of Acute Methyl Alcohol Toxic Encephalopathy

作　　者：彭育立[1] 刘红军[2] 张忠林[2] 于成福[1] 骆惠华[1] 周元敏[1] 

机构地区：[1]广州市第十二人民医院(化学中毒救援中心)放射科,广州510620 [2]广东省人民医院放射科

出　　处：《放射学实践》2005年第4期327-329,共3页Radiologic Practice

摘　　要：目的:分析甲醇中毒患者的颅脑CT及MR表现,以提高影像诊断水平。方法:搜集40例甲醇中毒患者的颅脑及眼部的CT和MR资料,回顾性分析其CT及MR表现。结果:40例中额顶叶白质、外囊壳核CT呈低密度及MR呈长或短T1 长T2 改变的18例,占45%。其中双侧外囊壳核CT呈低密度、MR呈长或短T1 长T2 改变共16例,占40%,右侧壳核出血1例。额、顶叶皮层下白质密度减低共6例,迟发(入院后1周)表现1例。双侧颞叶海马CT呈低密度、MR呈长T1 长T2 改变,共8例。红核、黑质边缘模糊共4例。视神经呈长T1 长T2 改变共8 例。结论:双侧外囊壳核出血性坏死、白质水肿为急性甲醇中毒性脑病的CT及MR主要表现,少数有外囊壳核出血表现。视神经筛板板层内段早期表现为水肿、晚期表现为视神经萎缩。MR检查病灶更加明确,更有特征性。Objective:To analyze the CT and MR manifestations of methyl alcohol toxic encephalopathy and to improve the diagnosing capability.Methods:40 patients with methyl alcohol intoxication were collected in this study,CT and MR data of brain were retrospectively studied.Results:CT low density and MR long/short T 1 and long T 2 were observed in frontal-parietal white matter and putamen in 18 patients (45%).In these 18 cases,bilateral putamen changes were found in 16 patients (40%);putamen hemorrhage of right side was found only in 1 patients;CT low density lesions in subcortical white matter of bilateral frontal and parietal lobes were found in 6 patients;delayed manifestation in 1 case;bilateral temporal lobes and hippocampi abnormalities in 8 cases;hazziness of the border of red nucleus and substantia nigra in 4 cases;long T 1 and long T 2 signal of optic nerves were observed in 8 cases.Conclusion:The main CT and MR manifestations of acute methyl alcohol toxic encephalopathy are hemorrhagic necrosis and white matter edema,substantive hemorrhage can be found occasionally.Optic nerve edema in early stage and atrophy in later stage can be observed. MR is more sensitive and specific than CT to find the lesions.

关 键 词：中毒 甲醇 神经系统 体层摄影术 X线计算机 磁共振成像 

分 类 号：R445[医药卫生—影像医学与核医学]