冠心病患者血栓前状态与肱动脉血流依赖性舒张功能的关系  

Relationship between Post-thrombosis and Endothelial Dilation Function with Coronary Heart Disease

作　　者：何丽林 

机构地区：[1]虎林迎春林业局职工医院,黑龙江虎林158403

出　　处：《黑龙江医学》2005年第4期248-249,共2页Heilongjiang Medical Journal

摘　　要：目的　探讨冠心病患者血栓前状态与内皮舒张功能的关系的意义。方法　参照Celemajer介绍的方法检测肱动脉血流依赖性舒张功能。结果　冠心病组与对照组相比vWF、GMP - 14 0、FIB、DD、FMD之间均有显著差异,冠心病病人中FMD与vWF、GMP - 14 0、FIB之间呈现负相关。结论　肱动脉血流依赖性舒张功能检测结合血栓前状态分子标记物可有效地判断冠心病患者的病情及指导治疗。Objective To investigate the relationship between postthrombosis and endothelial dilation function and its clinical significance in patient with coronary heart disease (CHD). Methods According to Celemajer's method to examine brachial flowing-mediated-dilation function. Results vWF, GMP-140, FIB, DD and FMD had significant difference between CHD group and control group. Conclusion Brachial flowing-mediated-dilation function and postthrombosis might have clinical value for diagnosis and treatment of CHD.

关 键 词：内科学 冠心病 肱动脉 舒张功能 血栓前状态 分子标记物 

分 类 号：R541.4[医药卫生—心血管疾病]