对二甲氨基苯甲酸的合成  

Synthesis of p-(Dimethylamino)-benzoic Acid

作　　者：谢川[1] 刘建[2] 李海燕[1] 

机构地区：[1]四川大学化工学院,四川成都610065 [2]中国工程物理研究院西南计算中心,四川绵阳621900

出　　处：《合成化学》2005年第2期201-203,共3页Chinese Journal of Synthetic Chemistry

摘　　要：以对二甲氨基苯甲醛为原料,Ag2O为催化剂,空气为氧化剂,合成了紫外吸收剂对二甲氨基苯甲酸,其结构经UV,IR和MS确认。用正交实验设计确定了最佳工艺条件:对二氨基苯甲醛3g(20mmol),Ag2O0.3g(对二甲氨基苯甲醛质量的10%),KOH4.5g(浓度3%),在60℃反应24h,收率75.8%。p-(Dimethylamino)-benzoic acid was synthesized from p-(dimethylamino)-benzaldehyde using Ag 2O as a catalyst and air as a oxidant. The structure was confirmed by UV, IR and MS. The optimal operation conditions were determined through orthogonal experiment: p-(dimethylamino)-benzaldehyde 3 g(20 mmol), Ag 2O was 10%[mass of p-(dimethylamino)-benzaldehyde] , KOH was 4.5 g(concentration 3%), the reaction temperature was 60 ℃ and the reaction time was 24 h, the yield was 75.8%.

关 键 词：二甲氨基苯甲酸 二甲氨基苯甲醛 UV吸收剂 合成 

分 类 号：O625.51[理学—有机化学] O621.3[理学—化学]