N-(4-芳基-噻唑-2-基)-ω-(1H-苯并三唑-1-基)苯乙酮腙类衍生物的合成  

Synthesis of New N-(4-Aryl-thiazol-2-yl)-ω-(1H-benzo[d]-1,2,3-triazol-1-yl)acetophenone Hydrazones

作　　者：孙亚栋[1] 刘方明[1] 解正峰[1] 陈家胜[1] 

机构地区：[1]新疆大学化学与化工学院乌

出　　处：《有机化学》2005年第4期449-453,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.29702007;20162004)资助项目.

摘　　要：以苯并三唑为原料与ω-溴代芳基乙酮缩合得ω-(1H-苯并三唑-1-基)芳基乙酮,再与硫代氨基脲缩合得到新的缩氨基硫脲.然后分别与5种ω-溴代芳基乙酮环化得到一系列新的含苯并三唑和噻唑环的苯乙酮腙类Schiff碱.其结构经IR,1HNMR,13CNMR和MS及元素分析确证.Three new substituted acetophenone thiosemicarbazones have been synthesized by condensation reaction of acetophenones with thiosemicarbazide, which reacted with ω-bromoacetophenone in EtOH under refluxing to give a series of acetophenone hydrazone derivatives. Their structure were characterized by ele-mental analysis, IR , 1H NMR, 13C NMR and MS spectra.

关 键 词：苯并三唑 苯乙酮 芳基 腙类 衍生物 Schiff碱 合成 缩氨基硫脲 硫代氨基脲 ^13C 元素分析 NMR 噻唑环 ^1H 缩合 溴代 IR 

分 类 号：TQ463.53[化学工程—制药化工]