电子阴道镜对尖锐湿疣亚临床感染形态学诊断的探讨  

Study on Morphology Diagnosis of Condyloma Acuminata by Using Electron Colposcope

作　　者：王琪[1] 胡亚红[1] 王婷琳[1] 陈孟禄[1] 

机构地区：[1]民航总医院皮肤科,北京100025

出　　处：《中国皮肤性病学杂志》2005年第4期220-222,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨电子阴道镜对尖锐湿疣亚临床感染进行形态学诊断的可行性。方法①用电子阴道镜对96例尖锐湿疣患者无肉眼可见损害处进行检查。②可疑损害形态分型做醋酸白试验及免疫组化检测人乳头瘤病毒。结果96例患者发现可疑亚临床损害268个,大致分为斑片型、棘刺型、血管型三型。醋酸白试验阳性率72.8%,其中血管型损害仅为30.6%,与斑片型(96.5%)、棘刺型(90.5%)的阳性率差异有显著性(P<0.05)。免疫组化人乳头瘤病毒检测总阳性率45.2%,三型间差异无显著性(P>0.05)。结论电子阴道镜可以从形态学上较准确的诊断尖锐湿疣的亚临床损害,尤其可发现醋酸白试验阴性的损害,故有更高的检出率。Objective To discuss the feasibility on morphology diagnosis of condyloma acuminata(CA) subclinc papillomavirus infection(SPI) by using electron colposcope observation.Methods ①Detect possible lesions in 96 patients of CA by using electron colposcope.②Assess the type of CA infection .Carry out acetic acid test and SP immunohistochemiscal assay to detect HPV infections in possible lesions.Results 268 possible lesions had been found in 96 patients.These 268 lesions could be divided into three major types named patch,spine and vascular.The positivity rate of acetic acid test was 72.8%(patch 96.5%,spine 90.5%,vascular 30.6%).The positivity rate was relatively low with vascular type as compared with the other two types(P<0.05).The positive rate using the method of immunohistochemistry in HPV detection was 45.2%.There was no significant difference of three types(P>0.05).Conclusion The electron colposcope observation is a more reliable method of detecting from a morphological aspect and diagnosing CA of subclinic papillomavirus infection than acetic acid test.

关 键 词：电子阴道镜 尖锐湿疣 亚临床感染 醋酸白试验 免疫组化 

分 类 号：R752.5[医药卫生—皮肤病学与性病学]