老年血液透析患者死亡相关因素分析  

Analysis on the risk factors related to death of elderly hemodialysis patients

作　　者：张利[1] 陈香美[1] 申力军[1] 张冬[1] 

机构地区：[1]解放军总医院肾科解放军肾脏病中心暨重点实验室,北京100853

出　　处：《中国老年学杂志》2005年第4期359-361,共3页Chinese Journal of Gerontology

基　　金：国家重点基础研究发展规划项目资助课题(编号G2000057000);国家自然科学基金委员会"创新研究群体科学基金"(30121055)资助

摘　　要：目的探讨老年尿毒症血液透析患者的死亡相关因素。方法回顾总结121例老年血液透析患者的发病、转归及死亡相关因素,对比观察老年组与非老年组透析疗效。结果缺血性肾损害、慢性肾小球肾炎及药物性肾损害为老年血液透析患者的前三位病因,老年组的透析充分性与非老年组无明显差异。糖尿病死亡率明显高于其他疾病,多元回归表明低蛋白血症及C反应蛋白升高是老年血液透析患者的危险因素。结论继发性肾脏疾病成为老年人尿毒症的主要病因,营养不良及炎症是导致老年透析患者死亡的独立相关因素。Objective To explore the risk factors related to death of elderly hemodialysis patients with uremia. Methods The incidence, outcome and risk factors related to death of 121 elderly hemodialysis patients were analyzed retrospectively, and the therapeutic effect were compared between elderly hemodialysis patients and non-elderly ones. Results Ischemic renal damage was the most common cause for end stage renal disease (ESRD) in elderly patients, followed by primary glomerular diseases and then drug-induced nephropathies. There was no significant difference in dialysis adequacy between elderly patients and non-elderly ones. The mortality of patients with diabetic nephropathy was significantly higher than that of patients with the other diseases. Regressive analysis indicated that hypoproteinemia and elevation of C reactive protein should be the risk factors of elderly hemodialysis patients. Conclusions Secondary renal disease should be the main pathogeny of the elderly with uremia, malnutrition and inflammation should be independent related risk factor resulting in death of hemodialysis patients.

关 键 词：老龄 尿毒症 血液透析 

分 类 号：R339.38[医药卫生—人体生理学]