条件培养液中的活性组分  

The Active Components of Conditioned Medium

作　　者：金洁[1] 史小林[1] 

机构地区：[1]首都医科大学生殖医学研究中心,北京100054

出　　处：《细胞生物学杂志》2005年第2期133-137,共5页Chinese Journal of Cell Biology

基　　金：北京市教委资助项目(No.KM200310025289)~~

摘　　要：条件培养液中含有细胞分泌的活性物质,因此,条件培养液可再现体外培养细胞或组织的微环境,促进或抑制来源不同的细胞或组织的生长、增殖和分化,也被用于研究各种生理或病理现象的机制。当前,国内外研究较多的有乳腺癌细胞系MDA-MB-231细胞、骨髓内皮细胞、坐骨神经和肝细胞等的条件培养液。Conditioned medium contains many active compounds that are secreted by the cells. Hence, it can promote or suppress the cells or the tissues’growing, proliferating and differentiating with the ability to reappear their microenvironment. In addition, it is used to elucidate the mechanisms of various physiological and pathological phenomena. Currently, the conditioned mediums of MDA-MB-231 cells, bone marrow endothelial cells, cultured- sciatic nerves and hepatocytes get more attention. These topics will be reviewed in this article.

关 键 词：条件培养液 活性组分 体外培养 MDA-MB-231细胞 骨髓内皮细胞 坐骨神经 肝细胞 

分 类 号：Q813.1[生物学—生物工程]