海洛因滥用者血清吗啡浓度放免测定  

RIA DETERMINATION OF MORPHINE CONCENTRATION IN SERUM OF HEROIN ABUSERS

作　　者：周君富[1] 丁德云[1] 刘前进[1] 

机构地区：[1]浙江医科大学附属第二医院脑研室,浙江医科大学附属第一医院核医学科

出　　处：《浙江医科大学学报》1994年第1期14-16,共3页

摘　　要：作者用放射免疫分析法测定３８例海洛因滥用者和６０例健康成人血清吗啡浓度，结果表明，海洛因滥用者组的血清吗啡平均浓度显著较健康成人组高（Ｐ＜０．０００１），且海洛因滥用者的血清吗啡浓度随海洛因日吸食量及吸食史的增加而升高，呈一定程度的直线正相关（ｒ＝０．８２０７，Ｐ＜０．０００１；ｒ＝０．７７３６，Ｐ＜０．０００１）。提示血清吗啡浓度的放射免疫测定可作为判断海洛因滥用者的可靠指标。The serum level of morphine in 38 heroin abusers and 60 healthy subjects was determined with RIA. The average serum morphine concentration of the heroin abusers was higher than that of the healthy subjects (P<0. 0001).The serum morphine concentration in the heroin abusers varied with different doses and duration of heroin administration,revealing linear positive correla tions (r=0. 8207,P<0.0001;r=0. 7736, P<0. 0001).It suggested that RIA for serum morphine concentration could be used as a reliable index for the judgement of heroin abusers.

关 键 词：物质滥用 放射免疫测定 二乙酰吗啡 

分 类 号：R446.6[医药卫生—诊断学]