瑞芬太尼复合丙泊酚用于无痛人工流产术的效果评价  

Combined remifentanil and propofol used in anesthesia for artificial abortion.

作　　者：方光光[1] 刘志恒[1] 陈虹[1] 卢健芳[1] 曾果花[1] 李锦莲[1] 

机构地区：[1]深圳市第二人民医院,深圳518038

出　　处：《华中医学杂志》2005年第2期91-92,共2页Central China Medical Journal

摘　　要：目的　比较单纯丙泊酚和瑞芬太尼复合丙泊酚用于无痛人工流产手术的作用。方法　将80例早孕妇女随机分为两组,分别用丙泊酚2 mg/kg(P组)和瑞芬太尼1.5μg/kg复合丙泊酚2 mg/kg(R+P组)诱导,术中均用丙泊酚3 mg/(kg·h)维持,病人躁动时添加丙泊酚。监测术中心率、血压,记录手术时间、丙泊酚总用量、苏醒时间、离开手术室时间,以及妇科情况和病人及妇科医师满意度评分。结果　两组术中生命体征、手术时间以及妇科情况无显著差异。R+P组丙泊酚用量显著低于P组,而苏醒时间和离开手术室时间明显短于P组。结论　在无痛人流手术中,瑞芬太尼复合丙泊酚较单纯丙泊酚有利于减少麻醉药物用量,加快病人苏醒。Objective To compare pure propofol and combined remifentanil and propofol used in anesthesia for artificial abortion.Methods Eighty patients consented for artificial abortion were randomized into two groups: 2 mg/kg propofol (group P) or combined 1.5 μg/kg remifentanil and 2 mg/kg propofol (group R+P) were administered respectively. Continuous 3 mg /(kg·h) propofol were used for both groups, and bolus propofol was added when the patient moved. Intraoperative heart rate and blood pressure were monitored. Operation time, total consumption of propofol, time of wakening, time of stay in the operation room, gynecological findings, and satisfactory rate of both the gynecologists and the patients were recorded.Results There were no difference between the two groups in intraoperative vital signs, operation time and gynecological findings. Total consumption of propofol was less in group R+P than that in group P(P< 0.05 ). Whereas time of wakening and time of stay in the operation room in group R+P were shorter than those in group P (P< 0.05 ). Satisfactory rate of the gynecologists was higher in group R+P.Conclusion Combined remifentanil and propofol can lessen the consumption of anesthetics and fasten the patients wakening compared to propofol alone.

关 键 词：瑞芬太尼 丙泊酚 无痛人工流产术 效果评价 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]