左旋甲状腺素对亚临床甲状腺功能减退患者的治疗作用  

Effects of Levothyroxine Treatment on Patients with Subclinical Hypothyroidism

作　　者：李青菊[1] 李鹏诺[1] 田晨光[1] 张苏和[1] 李凤良[1] 

机构地区：[1]郑州大学第二附属医院内分泌科,郑州市450014

出　　处：《医药论坛杂志》2005年第5期18-19,22,共3页Journal of Medical Forum

摘　　要：目的观察小剂量左旋甲状腺素对亚临床甲状腺功能减退症患者的治疗作用。方法对30例亚临床甲状腺功能减退患者,给予小剂量左旋甲状腺素治疗,比较治疗前后患者的临床症状和血脂的变化。结果治疗后患者血清总胆固醇、低密度脂蛋白及载脂蛋白B比治疗前明显降低(P<0.05),部分患者的症状缓解。结论小剂量左旋甲状腺素可明显降低亚临床甲状腺功能减退患者的血脂,缓解部分患者的临床症状。Objective To investigate the effect of low dose levothyroxine treatment on the patients with subclinical hypot hyroidism.Methods 30 subclinical hypothyroidism patients were trea ted by low dose levothyroxine,after treatment the serum lipids and thesymptoms were compared with those before treatment.Results After treatment the levels of serum total cholesterol,low densitylipo-protein and ApoB were significantly lower than those before treatment(P<0.05),patients showed a-melioration in symptoms.Conclusion The low dose levothy roxinetreatment on the patients with subclinical hypothyroidism could sinificantly decrease the serum lipid level and ameliorate the symptom.

关 键 词：甲状腺素 甲状腺功能减退 亚临床 血脂 症状 

分 类 号：R581.2[医药卫生—内分泌]