腹膜透析患者抑郁症状的影响因素  

Depression in Patients Receiving Peritoneal Dialysis

作　　者：刘希会[1,2] 胡昭[2] 汪涛[1] 

机构地区：[1]北京大学第一医院肾内科,北京大学肾脏病研究所 [2]山东大学齐鲁医院肾内科

出　　处：《中国心理卫生杂志》2005年第4期230-232,共3页Chinese Mental Health Journal

基　　金：教育部长江学者奖励计划和教育部教育振兴行动计划专项基金(985工程)资助。

摘　　要：目的:探讨腹膜透析病人抑郁及影响因素.方法:用汉密顿抑郁量表(HAMD)17项版本评估99例透析大于3个月,临床状况稳定的门诊腹膜透析病人的抑郁症状,用Charlson合并症指数评估病人合并症情况,同时调查睡眠质量、躯体症状、社会支持等因素和有关的生化指标.结果:抑郁评分均值7.37±5.38,其中10～13分11例(11.2%),14～17分9例(9%),大于17分5例(5.1%).抑郁评分与合并症指数正相关,与躯体症状负相关,与睡眠质量负相关.抑郁评分与血清白蛋白(ALB)、血红蛋白(Hb)、尿素清除指数(Kt/Vurea)相关性无统计学意义.抑郁评分与经济收入、社会支持等呈负相关,多元线性回归分析结果表明,躯体症状、睡眠质量、肾脏疾病所致负担是抑郁的预测因子.结论:腹膜透析病人中抑郁情绪多见,躯体症状、睡眠质量、疾病所致负担等是抑郁情绪的影响因素.Objective: To analyze the possible factors associated with depression in peritoneal dialysis (PD) patients.Methods: 99 patients who had received PD for a minimum duration of 3 months were recruited in this study. Depression was evaluated using HAMD. Comorbidity was evaluated using Charlson Cormorbidity Index (CCI). Patient's somatic symptoms, quality of sleep, burden of kidney disease, educational level and annual income, and social support were also evaluated. Meanwhile, biochemistry and dialysis adequacy were recorded. Results: The mean depression score of our patients was 7.37±5.38. 11 of our patients scored 10~13(mild), 9 scored 14~17(mild to moderate), and 5 had scores more than 17(moderate to severe). 25.3% of our patients had various degree of depression. The depression score was positively correlated with the CCI and negatively correlated with the somatic symptoms, quality of sleep, psychosocial factors. (all P<0.05). Patients with higher annual income had lower depression scores. Conclusion: This study has demonstrated that depression is commonly encountered in PD patients. Somatic symptoms, quality of sleep and burden of kidney disease are the factors influencing depression.

关 键 词：腹膜透析 抑郁 影响因素 临床心理学 断面调查 

分 类 号：R459.5[医药卫生—治疗学]