酸性膨润土催化合成乙酰水杨酸研究  

Studies on synthesis of acetylsalicylic acid catalyzed by acid bentonite

作　　者：陈志勇[1] 何奕波[2] 

机构地区：[1]信阳师范学院化学化工学院,河南信阳464000 [2]信阳职业技术学院生化系,河南信阳464000

出　　处：《信阳师范学院学报（自然科学版）》2005年第2期195-197,221,共4页Journal of Xinyang Normal University(Natural Science Edition)

基　　金：河南省科技攻关项目(991200220)

摘　　要：以水杨酸和乙酸酐为原料,在自制酸性膨润土催化下合成了乙酰水杨酸;探讨了催化剂的结构特征及最佳合成条件.结果表明:酸性膨润土对乙酰水杨酸的合成具有良好催化活性;在水杨酸与乙酸酐投料比为1∶ 3.6,酸性膨润土加入量等于5%水杨酸投料量(质量)和85～90 ℃下,催化反应0.5～1.0 h,产物收率可达90.44%.Acetylsalicylic acid was synthesized from salicylic acid and acetic anhydride catalyzed by acid bentonites. The structural features of bentonite and the optimum synthesis conditions of acetylsalicylic acid were investigated in details. The results obtained show that the acid bentonites has good catalytic behavior on synthesis of acetylsalicylic acid. The yield rate of 90.44% can be obtained under the reaction conditions as follows: the ratio of salicylic acid and acetic anhydride is 1∶3.6, the ratio of salicylic acid and acid bentonites is 1∶0.05, reaction temperature and time are 85~90 ℃ and 0.5~1.0 h, respectively.

关 键 词：水杨酸 乙酸酐 乙酰水杨酸 酸性膨润土 

分 类 号：TQ225.4[化学工程—有机化工]