大豆苷元对豚鼠离体胆囊自发性收缩运动的影响  

Constriction Effect of Daidzein on Guinea Pig's Gall Bladder the Spontaneous Constriction

作　　者：曾靖[1] 李冬莲[2] 邱峰[3] 李良东[1] 黄志华[1] 

机构地区：[1]赣南医学院药理,生理学教研室 [2]赣州市人民医院耳鼻喉科,江西赣州341000 [3]沈阳药科大学植化教研室,辽宁沈阳110016

出　　处：《赣南医学院学报》2005年第1期1-2,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：江西省卫生厅中医药科研基金课题 (2 0 0 2A2 0 )

摘　　要：目的:研究大豆苷元对豚鼠离体胆囊自发性收缩运动的影响。方法:采用豚鼠离体胆囊肌条收缩描记法,观察不同浓度的大豆苷元其自发性收缩的影响。结果:大豆苷元显著抑制豚鼠离体胆囊肌条自发性收缩活动,使收缩力降低,紧张性下降,且呈量效反应关系。此外,还可对抗乙酰胆碱、组胺引起的离体胆囊肌条收缩运动。结论:大豆苷元显著抑制豚鼠离体胆囊自发性收缩。Objective:To study the effect of Daidzein on gall bladder the spontaneous constriction .Methods:To study how Daidzein antagonized the gall bladder constriction of guinea pig induced by acitylcholine,histamine;To study how Daidzein antagonized the gall bladder constriction of guinea pig induced by histamine.Results:It has been found that Daidzein is remarkedly effective in antagonizing the gall bladder constriction of guinea pig induced by acitylcholine,histamine. Conclusion: Daidzein has an obvious antagonized effect on the spontaneous constriction of gall bladder of guinea pig.

关 键 词：大豆苷元 胆囊 自发性收缩 

分 类 号：R965[医药卫生—药理学]