Synthesis and Crystal Structure of N-methyl-9-(4-bromophenyl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione under Microwave Irradiation  

作　　者：HUAGuo-Ping ZHANGXiao-Jing TUShu-Jiang ZHUSong-Lei LITuan-Jie ZHUXiao-Tong ZHANGJin-Peng 

机构地区：[1]XuzhouInstituteofArchitecturalTechnology,Xuzhou,Jiangsu221008,China [2]DepartmentofChemistry,XuzhouNormalUniversity,KeyLaboratoryofBiotechnologyonMedicalPlant,Xuzhou,Jiangsu221116,China

出　　处：《Chinese Journal of Structural Chemistry》2005年第4期399-402,共4页结构化学（英文）

基　　金：This work was supported by the National Natural Science Foundation of China (No. 20372057); Natural Science Foundation of Jiangsu Province (No. BK2001142); the Suzhou University Organic Synthesis Open Laboratory of Jiangsu Province (No. S81091 11) and the Key Lab of Biotechnology for Medicinal Plants of Jiangsu Province (No. 01AXL 14)

摘　　要：The crystal structure N-methyl-9-(4-bromophenyl)-1,8-dioxo-1,2,3,4,5,6,7,8,9,10- decahydroacridine(C20H20BrNO2) was determined by single-crystal X-ray diffraction analysis. It belongs to P21/n space group, with a = 10.7999(18), b = 13.845(3), c = 11.4031(3) ?, β = 99.324(4)°, Dc = 1.525 g/cm3, Z = 4, λ = 0.71070 ?, μ(MoKα) = 2.455 mm-1, Mr = 386.28, V = 1682.5(5) ?3, F(000) = 792, the final R = 0.0463 and wR = 0.1053. In the crystal structure, the pyridine ring adopts a boat conformation, the two six-numbered rings fused with pyridine ring adopt twisting boat con- formation.The crystal structure N-methyl-9-(4-bromophenyl)-1,8-dioxo-1,2,3,4,5,6,7,8,9,10- decahydroacridine(C20H20BrNO2) was determined by single-crystal X-ray diffraction analysis. It belongs to P21/n space group, with a = 10.7999(18), b = 13.845(3), c = 11.4031(3) ?, β = 99.324(4)°, Dc = 1.525 g/cm3, Z = 4, λ = 0.71070 ?, μ(MoKα) = 2.455 mm-1, Mr = 386.28, V = 1682.5(5) ?3, F(000) = 792, the final R = 0.0463 and wR = 0.1053. In the crystal structure, the pyridine ring adopts a boat conformation, the two six-numbered rings fused with pyridine ring adopt twisting boat con- formation.

关 键 词：ACRIDINE synthesis microwave irradiation crystal structure 

分 类 号：O623.59[理学—有机化学] O76[理学—化学]