RP-HPLC比较蒺藜全草和果实中的主要甾体皂苷元成分  

Comparison of main saponins from fruits and whole plant of Tribulus terrestris L. by RP-HPLC

作　　者：牛伟[1] 瞿伟菁[1] 曹群华[1] 邓云霞[1] 刘超[1] 郭扬[1] 

机构地区：[1]华东师范大学生命科学学院,上海200062

出　　处：《中成药》2005年第4期456-458,共3页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金资助项目(30370158)

摘　　要：目的:比较蒺藜全草和果实中主要甾体皂苷元成分,探索蒺藜中的确切指标成分。方法:采用反相高效液相色谱法,利用C18柱和示差折光检测器,定量比较了蒺藜(TribulusTerrestrisL. )全草和果实中的主要甾体皂苷元成分。结果:全草与果实中的海可皂苷元含量相近而替告皂苷元含量有显著差异 (P<0. 01)。结论:替告皂苷可能是蒺藜全草的主要指标成分。AIM: To compare the main saponins extracted respectively from the fruits and the whole plant of Tribulus terrestris L. and study its marked component. METHODS: Using C 18 ODS column and Refractive Index Detector, we compared the main saponins extracted respectively from the fruits and the whole plant of Tribulus terrestris L. in quantity by RP-HPLC. RESULTS: Tigogeniin contents from herb and its fruit had distinct difference between them (P<0.01) while hecogenin content is similar. CONCLUSION: Tigogenin is suggested to be the marked component of Tribulus terrestris L.

关 键 词：蒺藜 皂苷 海可皂苷元 替告皂苷元 RP—HPLC 

分 类 号：R284.1[医药卫生—中药学]