用分光光度法测定复方药物安痛定片、阿司匹林和感克片中非那西丁含量  

The Quantitative Measuring of Phenacetin in Compound Medicament Antongding、Aspirin、Keganming By Spectrophotometry

作　　者：高元萍[1] 倪春娟[2] 郑王巧[1] 

机构地区：[1]长治医学院药学系药物分析教研室,046000 [2]长治医学院生物学教研室,046000

出　　处：《长治医学院学报》2005年第1期5-7,共3页Journal of Changzhi Medical College

摘　　要：目的:为临床药物分析提供一种简便、快速的分析方法。方法:准确量取复方阿司匹林、安痛定、感克三种滤液1 .5mL和非那西丁标准溶液适量,用紫外-可见分光光度计测吸光度A。结果:三种样品的平均回收率分别为:1 0 0 .6%、1 0 0 .1 %、99.2 7%。标准偏差为0 .35 5 %、0 .2 63%、0 .5 98%。结论:本方法快速、简便,所用试剂简单,适用于复方药物中非那西丁单一组分含量的测定。Objective: To provide a kind of simple and quickly analytical method for the clinical medicine analyzation. Methods: Accurately take three kinds of filtrate 1.5 mL and the right amount of phenacetin standard aqua , measuring the degree of the absorbency A with ultraviolet―radiationvisible light spectrophotometry。 Result:The average recovery rate of three kinds of samples respectively is:100.6%,100.1%,99.27%. The standard deviation is 0.355%,0.263%,0.598%.Conclusion:This method is fast and simple. be applicable to the measurement of phenacetin from compound prescribe medicine.

关 键 词：分光光度法 阿司匹林 安痛定 感克 

分 类 号：R927.1[医药卫生—药学]