住院肝炎患者病毒检测及重叠感染状况分析  

Analysis on classification of hepatitis patients and superinfection condition

作　　者：张涛 高眉扬[1] 赵琦[1] 曹海俊[1] 徐飚[1] 姜庆五[1] 

机构地区：[1]复旦大学公共卫生学院流行病学教研室,上海200032

出　　处：《中国公共卫生》2005年第4期427-428,共2页Chinese Journal of Public Health

基　　金：厦门大学细胞生物学与肿瘤细胞工程教育部重点实验室支持

摘　　要：目的　了解上海地区以往肝炎患者的肝炎型别和重叠感染状况。方法　采用ELISA法对从复旦大学公共卫生学院血清库中抽取的上海某区医院 90年代初期肝炎患者的血清进行HAVIgM、HCVIgG、HEVIgM和HEVIgG的检测。 结果　在上海 114 3名肝炎患者中 ,HAVIgM、HBV、HCVIgG、HEVIgM和HEVIgG的阳性率分别为 5 2 .1% ,5 3 .6 % ,1. 3% ,17. 8%和 70 . 4 % ,有多重感染的患者数为 74 6人 ,约占总病例数的 6 5. 4 % ,其中甲、乙、丙、戊型肝炎的重叠感染率分别为 6 1 .4 % ,6 9 .3% ,0 . 9和 17.4 %。结论　肝炎患者的多重感染情况普遍存在 ,甲乙型重叠感染可能影响乙型肝炎病毒感染的复制 ,对健康的危害较为严重。Objective To investigate the classification of hepatitis patients and the condition of superinfection.Methods The sera came from sera bank of School of Public Health,Fudan University,and all of the hospitalize hepatitis patients in shanghai in 1990s were determined by ELASA for anti-HAV IgM,anti-HCV IgG,anti-HEV IgM and IgG.Results In the 1143 patients,the positive rate of HAV IgM,HBV,HCV IgG,HEV IgM and HEV IgG were 52.1%,53.6%,1.3%,17.8% and 70.4% respectively.And the superinfection patients came up to 746,about 65.4%.The superinfection rates of hepatitis A,B,C,E respecifically equal to 61.4%,69.3%,0.9 and 17.4%.Conclusion The superinfection is very common among the hepatitis patients.The interaction of HAV and HBV may restrain the replication of HBV and people health is threatened.

关 键 词：肝炎 重叠感染 流行病学 

分 类 号：R183[医药卫生—流行病学]