抗小麦赤霉病抗生素861-A的提取、纯化及理化性质  

ISOLATION, PURIFICATION AND PHYSICO-CHEMICAL PROPERTIES OF ANTIBIOTIC 861-A USED FOR WHEAT SCAB CONTROL

作　　者：金同铭 宋家祥 李香玲[1] 卞则樑 柴文刚 贺玉珍[2] 张文信[2] 方一苇[2] 王光辉[2] 谢光华[2] 郑平[2] 

机构地区：[1]中国农业科学院原子能研究所 [2]中国科学院化学研究所

出　　处：《微生物学报》1989年第4期317-319,共3页Acta Microbiologica Sinica

摘　　要：小麦赤霉病是小麦的主要病害之一。在筛选防治小麦赤霉病的农用抗生素过程中,分离到链霉菌861菌株,定名为玫瑰皮黄链霉菌淡色变种(Streptomyces roseoalutaceus var,pallidus)。它的发酵液具有广谱的抗菌活性,经提取分离得到三个组份,其主要活性组分为抗生素861-A。经大面积作物防病药剂试验表明,对小麦赤霉病的防效达80—97%。本文报道其提取、分离及理化性质。Antibiotic 861 complex, isolated from Streptomyces roseoalutaceus var. pallidus by ion exchange chromatography, exhibits a broad antibacterial spectrum and a unique controlling efficiency to wheat scab, which is the major wheat disease in China. The complex was further purified by carbon column, acetone precipitation and CM-Sephadex G-25 ion exchange chromatography or high-performance liquid chromatography, and 861-A, the major effective component, was then obtained.Antibiotic 861-A is basic, hydroscopic white powder. It is very soluble in water and not soluble in normal organic solvents. A series of physico-chemical properties indicated that 861-A is a N-glycoside compound and identical with streptothricin F.

关 键 词：小麦赤霉病 抗生素 提取 

分 类 号：S482.7[农业科学—农药学]