3271例宫颈拭子支原体、衣原体检测及支原体耐药分析  

Analysis on Detection for Chlamydia Trachomatis and Mycoplasma and Drug Resistance of Mycoplasma in 3 271 Cases of Cervical Samples

作　　者：肖松舒[1] 邓新粮[1] 武继承[1] 

机构地区：[1]中南大学湘雅三医院妇产科,湖南长沙410013

出　　处：《医学临床研究》2005年第4期463-466,共4页Journal of Clinical Research

摘　　要：[目的]探讨宫颈解脲支原体(UU)、人型支原体(MH)和沙眼衣原体(CT)的感染情况及了解支原体耐药情况.[方法]应用金标法及支原体培养+药敏分析,对3 271例宫颈拭子进行CT、UU和MH三种病原体检测.[结果]①三种病原体总检出率为49.28%(1 612/3 271).其中单种病原体检出率为40.32%(1 319/3 271),混合感染率为8.96%(293/3 271);支原体检出率为40.51%(1 325/3 271);衣原体检出率为8.77%(287/3 271).②衣、支原体感染以21～40岁为主,占阳性患者的82.32%(1 327/1 612).③对支原体耐药率最高的是壮观霉素(耐药率>90%),其中人型支原体及解脲+人型混合感染者对壮观霉素、罗红霉素、红霉素等耐药率均>85%;对交沙霉素最敏感,其次是强力霉素.[结论]①UU、CT、MH是宫颈感染的主要病原体,其感染率UU>CT>MH.②支原体的耐药菌株常见,治疗应根据药敏结果选择敏感药物.To investigate the infection rates of Ureaplasma urealyticum(UU),Mycoplasma hominis(MH) and Chlamydia trachomatis(CT) in cervix uteri.The CT、UU and MH were detected in 3271 cases of cervical samples by using the culture for pathogens and golden-standard method.①Of the 3271 cases, the total infection rate of three pathogens was 49.28%(1 612/3 271), the rate of one pathogen infection was 40.32%(1 319/3 271),and the mixed infection rate was 8.96%(293/3 271); the infection rates of mycoplasm and chlamydia trachomatis were 40.51%(1325/3 271),8.77%(287/3 271) respectively.②The high risk age of mycoplasma and chlamydia trachomatis infection was from 21 to 40 years old,In this age range ,the positive rate was of 82.32% (1 327/1 612) .③The highest drug resistance rate of mycoplasma was actinospectacin (>90%),The resistance rates of the mycoplasma hominis and mixed infection of both UU and MH against actinospectacin,roxithromycin,erythromycin were all over 85%.The most sensitive antibiotics were josamycin,and then doxycycline.[Conclusion]①UU,CT and MH are the major pathogens in female cervix uteri.The range of infection rates from high to low are UU>CT>MH.②The drug resistance strains of mycoplasma was common.Therefore,we should choose the sensitive antibiotics according to the drug sensitivity test.

关 键 词：支原体属 衣原体属 药物耐受性 子宫颈 

分 类 号：R375[医药卫生—病原生物学] R374[医药卫生—基础医学]