Tei指数评价原发性高血压不同左室构型左室功能的研究  

Tei Index Assessment of Left Heart Function in Patients with Essential Hypertension with Different Pattern of Left Ventricular Geometric Model

作　　者：王洪霞[1] 高晓军[1] 蔡叶萍[1] 杨金秀 臧福波[1] 李峰春[1] 

机构地区：[1]大连市友谊医院超声科,辽宁省大连市116001 [2]寿光化龙医院

出　　处：《中国超声医学杂志》2005年第3期184-187,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的　探讨 Tei指数评价原发性高血压不同左室构型左室功能的临床价值。方法　原发性高血压患者 94例 ,按 Ganau分类法将原发性高血压分为 4型 :正常构型 ( 组 ,2 4例 )、向心性重构 ( 组 ,30例 )、向心性肥厚 ( 组 ,2 2例 )、离心性肥厚 ( 组 ,18例 ) ;正常对照组 30例。以常规超声心动图检查测量舒张末期室间隔、左室后壁厚度及左室内径 (IVS、L VPW、L VEDD) ,二尖瓣血流频谱图舒张早期与舒张晚期血流峰值比 (E/ A) ,二尖瓣前叶瓣环运动频谱图收缩期运动幅度 S峰及舒张早期与舒张晚期峰速比 (Ea/ Aa) ,左室射血分数 (EF)以及 Tei指数。结果　 、 、 组 E/ A均 <1(P<0 .0 5 ) ; 、 、 组与对照组比较 S值减低 (P<0 .0 5 ) ;Ea/ Aa均 <1(P<0 .0 5 ) ; 组 EF值低于正常对照组 (P<0 .0 5 ) ;高血压各组 Tei指数均较对照组增加 (0 .30± 0 .0 6 ,0 .4 3± 0 .1,0 .4 8± 0 .2 ,0 .5 1± 0 .12 ,0 .79± 0 .2 ;P<0 .0 5 ) ,呈递增趋势 , 组与 组 , 组与 、 、 组间差异有显著性意义 ;Tei指数和 S值 ,Ea/ Aa,EF均为轻度负相关 (r分别为- 0 .4 3、- 0 .33、- 0 .4 7,P值分别为 P<0 .0 0 1、P<0 .0 5、P<0 .0 0 1) ,Tei指数和 E/ A无相关性 (P>0 .0 5 )。结论　 Tei指数能简便、敏感。Objective To explore the clinical value of Tei index in assessment of left ventricular function in patients with essential hypertension Methods Ninety four patients with essential hypertension were enrolled According to Ganau categories,these patients were divided into four groups as follows:normal left ventricle(group Ⅰ,24 cases),concentric remodeling(group Ⅱ,30 cases),concentric hypertrophy(group Ⅲ,22 cases)and eccentric hypertrophy(group Ⅳ,18 cases),and 30 age matched healthy subjects as the contral group were included The end diastolic diameters of left ventricle(LVEDD),interventricular septum thickness(IVS),left ventricular posterior wall thickness(LVPW),E/A ratio(E/A) at mitral orifice,Ea/Aa ratio(Ea/Aa) and s at anterior mitral annulus were detected with Doppler tissue Imaging(DTI)and left ventricular ejection fraction(EF) and Tei index were measured Results Compared with the control group,E/A in group Ⅰ,Ⅱ,Ⅲ were lower than that in the normal Ea/Aa was<1 in all hypertension groups and s was decreased in groups Ⅱ,Ⅲ,Ⅳ EF was greatly decreased only in group Ⅳ.indices Tei of all patients were increased than that of the normal There was significant difference between group Ⅰand Ⅲ,as wall as between group Ⅳ and Ⅰ,Ⅱ,Ⅲ Tei index was negatively correlated with s,Ea/Aa,EF and was not correlated with E/A Conclusions Tei index was valuable and easy to estimate left ventricular systolic and diastolic functions with high sensitivity

关 键 词：左室功能 左室构型 指数评价 Tei指数 原发性高血压患者 超声心动图检查 正常对照组 左室后壁厚度 左室射血分数 高血压病患者 舒张晚期 舒张早期 向心性重构 向心性肥厚 血流频谱图 二尖瓣前叶 临床价值 舒张末期 左室内径 

分 类 号：R544.1[医药卫生—心血管疾病]