用高效液相色谱法同时测定九分散中麻黄碱和士的宁的含量  

Simultaneous Quantitative Determination of Ephedrine and Strychnine in Traditional Chinese Medicine "Joufensan" by HPLC

作　　者：陈发奎[1] 郭允珍[1] 鹿野美弘[2] 

机构地区：[1]沈阳药学院,110015 [2]日本北海道药科大学

出　　处：《中草药》1994年第11期571-572,577,共3页Chinese Traditional and Herbal Drugs

摘　　要：用高效液相色谱法在同一测定条件下，经一次测定同时对九分散中麻黄碱（ephedrine）和士的宁（strychnine）进行定量；并对样品提取方法进行了考察。为九分散的质量控制提供了一个简便、可靠的方法。A rapid, simple and sensitive method was establised for the evaluatiou of Chinese traditional medicine 'Joufenaan' by HPLC. Sample of 'Joufensan' was extracted by solvent, and the extraction analysed by HPLC using an inertsil ODS column with a solvent system, acetonitrile-water-phospboric acid-sodium dodecyl sulfate(38:62:0.1:0.5) at 40℃ and UV detector. The new method was reliable for the evaluation of ephedrine aud strychnine in 'Joufensan'.

关 键 词：九分散 麻黄碱 士的宁 高效液相色谱 含量 

分 类 号：R286.0[医药卫生—中药学]