薇乔网片及其胶原蛋白复合物在体外降解的研究  

In Vitro Degradation of Vicryl Mesh and Vicryl- Collagen Mesh

作　　者：刘德昌[1] 陈国平 

机构地区：[1]上海复旦大学金山医院骨科,上海200540 [2]日本国产业技术综合研究所

出　　处：《实用骨科杂志》2005年第2期125-127,共3页Journal of Practical Orthopaedics

摘　　要：目的　观察薇乔网片及其胶原蛋白复合物的降解。方法　将薇乔网片和胶原蛋白复合后的薇乔网片,剪成直径为1.5 cm大小,分为6组。浸没在高糖DMEM溶液中,每周取出1组,经过洗涤,冷冻,真空干燥后,称重。结果　薇乔网片和复合后的薇乔网片在4～5周内降解。结论　复合的薇乔网片可作为组织工程的支架材料。Objective To investigate the degradation of vicryl mesh and vicryl-collagen mesh. Methods Cut the vicryl mesh and vicryl-collagen mesh into 1.5 cm pieces in diameter, and divide it into 6 groups, then immersed in high glucose DMEM medium. Take one group out every week, then wash, froze and freeze-dry, weight it. Results Mesh will degrade within 4 and 5 weeks. Conclusion Vicryl-collagen mesh can be used as a tissue engineering scaffolds.

关 键 词：薇乔网片 蛋白复合物 体外降解 高糖DMEM 胶原蛋白 真空干燥 支架材料 组织工程 

分 类 号：R657.62[医药卫生—外科学] R151.2[医药卫生—临床医学]