倒挂牛乙醇提取物的抗炎症作用  

Antiinflammatory Effects of Alcohol Extract of Daoguaniou (Caesalpinia sepiaria var. pubescens)

作　　者：李乐[1] 庄斐尔[1] 李增利[1] 赵更生[1] 

机构地区：[1]西安医科大学临床药理研究所,710061

出　　处：《中草药》1994年第6期304-305,314,共3页Chinese Traditional and Herbal Drugs

摘　　要：倒挂牛乙醇提取物腹腔注射100mg／kg，对小鼠二甲苯耳部炎症、大鼠急性脑膜炎，大鼠角叉菜胶性足肿胀及蛋清性关节炎均有明显抗炎作用；小鼠腹腔注射LD50为303．7mg／kg，95％可信限为296．5±189．4mg／kg。An tiinflammatory effects of alcohol extract of Caesalpinia sepiarla Roxb. var. pubescent Tang et wang were shown by ip iujection. The extract significantly decreased xylene induced swelling of mice ear; carrageenin produced edema of hind paw in rats, and decreased volume of pleural exudate on carrageenin-induced acute pleurisy of rats. It also inhibited egg white induced arthritis iu rats.LD50 value is 303.7mg/kg by ip in mice, confidence limit of 95% is 296.5 ± 189.4mg/kg.

关 键 词：倒挂牛 乙醇提取物 抗炎作用 

分 类 号：R282.710.5[医药卫生—中药学]