“尿石清”冲剂预防尿草酸钙结石的临床研究  

Clinical study of"Niao shiqing" in the prevention of calcium oxalate stone of urinary

作　　者：李智刚[1] 陈腾[2] 

机构地区：[1]武警广东总队医院泌尿外科,广东广州510507 [2]武警广东总队医院药剂科,广东广州510507

出　　处：《武警医学院学报》2005年第3期207-208,211,共3页Acta Academiae Medicinae CPAPF

摘　　要：【目的】筛选一种安全有效的预防草酸钙尿石药物。【方法】选择既是食品(或食品添加剂)又可作药品的中西药物组方配成“尿石清”冲剂,对50例患者进行临床观察。【结果】患者口服“尿石清”冲剂5d,无任何不良反应。24h尿钙、磷和草酸含量明显下降(P<0.05);尿量、尿枸橼酸、尿镁和pH值显著升高(P<0.01)。【结论】“尿石清”冲剂能明显降低形成草酸钙结石盐类的浓度和饱和度,是一种很有前景的防石药物。To find the preventive effect to calcium oxalate stone and the side-effect of'Niao shiqing' throw clinical observation.50 cases of patient were selected for the experiment,before and after taking the drugs for 5 days,24 hours urine were collected,the ph,magnesium,citrate,calcium,phosphorus and oxalate were detected.All the patients had no side-effect,After having the drugs 5 days,the ph,citrate of urine had raised very significanly(P<0.01),the volume and magnesium raised significanly (P<0.05),which are restraining to the formation of calcium oxalate stone.The calcium and oxalate had lowed significanly(P<0.05).[Conclusion]'Niao shiqing' had cooperative effect in inhibiting the calcium oxalate growth.

关 键 词：“尿石清”冲剂 草酸钙 尿石 

分 类 号：R285.6[医药卫生—中药学]