黄芪多糖对急梗犬心的保护作用及其机制分析  

Protective Effects of Polysaccharide of Membranous Milkvetch (Astragalus membranaceus) on Acute Myocardially Infarcted Heart in Dog and Its Machanism of Action

作　　者：吕文伟[1] 雷春利[1] 陈羽[1] 江岩[1] 

机构地区：[1]白求恩医科大学,长春130021

出　　处：《中草药》1994年第11期586-589,共4页Chinese Traditional and Herbal Drugs

摘　　要：生理、生化、形态的17项检测指标均表明，黄芪多糖对急梗犬心有改善心肌收缩性能、缩小梗塞面积、减轻心肌损伤的作用。其机制可能与其抑制Na+-K+-ATP酶活性和抗自由基损伤作用有关。Seventeen physiological,biochemicaland morphological indexes consistently showed that Astragalus polysaccharide was able to enhance the myocardia contractility,attenuate the area of myocardial infarction, and reduce the degree of myocardial damage of myocardially infarcted dog heart in vivo.The mechanism might be related to the inhibition of Na+-Kr+ATPase activity & the anti-free-radical-damage action.

关 键 词：黄芪 多糖 心肌收缩 心肌梗塞 动物实验 

分 类 号：R259.422.2[医药卫生—中西医结合] R282.710.5[医药卫生—中医内科学]