烧伤感染阴沟肠杆菌的分型研究  

A study on the typing of Enterobacter cloacae in infection caused by burn

作　　者：张宏伟[1] 苏东 

机构地区：[1]天津市第四医院,西藏昌都地区人民医院300222 [2]中国医学科学院血液病医院检测中心,300020

出　　处：《河北医药》2005年第4期243-245,共3页Hebei Medical Journal

摘　　要：目的对烧伤感染阴沟肠杆菌进行种以下的鉴定,了解其在烧伤感染中的变化特点。方法　利用生物学分型、药敏谱分型及质粒分型对住院烧伤患者烧伤创面分泌物、血液、静脉导管尖端、尿液、粪便、空气、痂下组织中分离的阴沟肠杆菌进行分析。结果生物编码为30317703620和34307723620两种生物型分离率为最高。分出44种药敏谱型。分离出11种质粒谱型,质粒谱分型较为集中。结论烧伤感染阴沟肠杆菌可能仅是由少数型别菌种播散而来,生物分型、药敏谱模式分型不同是由于表型异质性而造成或存在流行质粒在烧伤感染阴沟肠杆菌不同型别间传播。阴沟肠杆菌的粪便-伤口传播可能是除了肠源性感染以外的一个很重要的传染途径。Objective To identify the different types of Enterobacter cloacae in infection caused by burn, in order to investigate its characteristics in bum infection. Methods The Enterobacter cloacae isolated from infective patients' secretion including burn surface,blood, venous ductus tips,urine,feces,air and the tissue under crust were analyzed by biologic typing,drug sensitive spectrum typing and plasmid typing methods. Results The isolation rates in two kinds of types were the highest,which were biological coding 30317703620 and 34307723620 respectively.There were 44 types of drug-resistance, 11 types of plasmid spectral pattern, and the latter were relatively localized. Conclusion The Enterobacter cloacae in infection caused by burn may be scattered from few bacterial types, and different types of biological and drug-resistance were due to the phenotype heterogeneity or due to prevalence plasmid spreading to different kinds of Enterobacter cloacae. Spreading type of excrement and urine may be the most important way besides enterogenic infection.

关 键 词：阴沟肠杆菌 烧伤感染 分型研究 生物学分型 创面分泌物 肠源性感染 药敏谱 变化特点 烧伤患者 质粒分型 静脉导管 痂下组织 生物分型 不同型别 传染途径 质粒谱 分离率 生物型 异质性 粪便 传播 

分 类 号：R378.2[医药卫生—病原生物学] R644[医药卫生—基础医学]