血清尿酸水平与冠心病的关系  

Relationship between serum uric acid and coronary heart disease

作　　者：王红[1] 孙静[2] 

机构地区：[1]天津市第五中心医院内科,300450 [2]天津胸科医院心内科

出　　处：《河北医药》2005年第4期256-257,共2页Hebei Medical Journal

摘　　要：目的探讨血清尿酸水平与冠心病的关系。方法经冠状动脉造影确诊的冠心病患者(冠心病组)75例和非冠心病患者(对照组)52例,检测二组的血清尿酸水平及相关血脂、血糖等生化指标。结果冠心病组血清尿酸水平显著高于对照组(369±77)μmol/L与(343±70)μmol/L,P<0.01;相关分析显示血清尿酸与冠脉狭窄指数呈正相关(P<0.05)。多元Logistic回归分析显示冠心病的发病与血清尿酸有关。结论血清尿酸水平与冠心病密切相关,高尿酸血症是冠心病的独立危险因素之一。Objective To investigate the correlation between serum uric acid ( SUA) and coronary heart disease (CHD) .Methods 75 patients with CHD proved by angiography and 52 control subjects without CHD were included in this study. SUA and blood lipid were detected. Results SUA levels in CHD patients were significantly higher than those of control subjects (369±77)μmol/L and (343±70)μmol/L, ( P < 0. 01). Correlation analysis showed that SUA levels were positively related to coronary stenosis index ( P < 0.05) . Through multivariate logistic regression analysis, SUA was related with the occurrence of CHD. Conclusion The SUA levels have a close relationship with CHD. Hyperuricemia is one of independent risk factors in CHD.

关 键 词：血清尿酸水平 多元LOGISTIC回归分析 经冠状动脉造影 冠心病患者 mol/L 独立危险因素 高尿酸血症 生化指标 狭窄指数 相关分析 对照组 正相关 显示 

分 类 号：R758.63[医药卫生—皮肤病学与性病学] R179[医药卫生—临床医学]