液体抗溶剂结晶制备聚碳酸酯微细粒子的研究  

Study on preparation of polycarbonate micro-particles by liquid anti-solvent crystallization

作　　者：黄捷[1] 蒋斌波[1] 王晓辉[1] 陈纪忠[1] 

机构地区：[1]浙江大学化学工程与生物工程学系,浙江杭州310027

出　　处：《浙江大学学报（工学版）》2005年第4期552-555,561,共5页Journal of Zhejiang University：Engineering Science

摘　　要：采用液体抗溶剂结晶(以无水乙醇为抗溶剂、三氯甲烷(氯仿)为溶剂)制备聚碳酸酯(PC)微细粒子.运用了透射电镜(TEM)、气体吸附分析仪、激光粒度分析仪、紫外可见分光光度计等分析手段来表征粒子的形貌、比表面积、粒径和粒度分布以及物质结构等.实验结果表明:在不同的条件下,可制备平均粒径为266～712 nm的聚碳酸酯微球,且粒径分布均匀.通过气体吸附分析可知:PC微粒具有较大的比表面积(36～51 m2/g).对加料速率、料液质量浓度、结晶温度等因素的考察说明以上各影响因素对PC粒子粒径有显著影响.该研究结果表明,反向加入、较快的加入速率、一定的体积比合适的料液质量浓度以及较低的结晶温度均有利于PC的细化.Polycarbonate (PC) microparticles were prepared by liquid anti-solvent crystallization using ethanol as anti-solvent and chloroform as solvent. Transmission electron microscope (TEM), gas sorption analyzer, laser diffraction-based particle size analyzer and UV-visible spectrophotometer was used to characterize and analyze the morphology, specific surface area, particle size, particle size distribution and structure of PC particles respectively. The mean particle diameter of PC spherical micro-particles ranged from 266-712 nm under different conditions with narrow particle size distributions. Gas sorption analysis showed that the prepared PC micro-particles had specific surface area of 36-51 m2/g. Experimental investigation on the effects of feed rate, solution concentration, temperature, etc. on PC micro-particle size revealed that higher feed rate, controlling volume ratio of solution to anti-solvent, solution concentration to a certain extent and lower crystallization temperature lead to reducing the size and distribution of PC micro-particles produced in the micronization process.

关 键 词：液体抗溶剂 结晶 聚碳酸酯 微细 

分 类 号：TQ323.41[化学工程—合成树脂塑料工业]