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作 者:俞景奎[1]
出 处:《山东医药》2005年第9期5-7,共3页Shandong Medical Journal
基 金:枣庄市科技局科技发展计划项目 (No.2 0 0 4-64 1)
摘 要:目的 探讨食管胃底静脉曲张的有效治疗方法。方法 将需施行贲门周围血管离断术的食管胃底静脉曲张患者6 1例随机分成两组。对照组30例,采用传统脾切除术+贲门周围血管离断术;观察组31例,在脾切除术后,紧贴胃食管壁行贲门周围血管离断术,保留自胃冠状静脉→食管旁静脉丛→奇静脉的侧支通畅;创面用生物胶止血,将医用涤纶片覆盖在剥离后的食管下段、胃底。结果 术后3、5年,两组食管静脉曲张程度均有明显差异(P <0 .0 1,P <0 .0 5 ) ;食管胃底静脉曲张再破裂出血率,观察组分别为6 .5 % (2 / 31)、9.7% (3/ 31) ,对照组分别为30 % (9/ 30 )、5 3.3% (16 / 30 ) ,两组相比均有明显差异(P <0 .0 5 ,P <0 .0 1)。术后5年食管胃底静脉曲张再破裂出血致死率,观察组为3.2 % (1/ 31)、对照组为2 3.3% (7/ 30 ) ,两组相比P <0 .0 5。结论 紧贴胃食管壁的贲门周围血管离断术联合涤纶片覆盖,能有效阻止食管胃底周围新生侧支循环的建立,明显降低贲门周围血管离断术后食管、胃底静脉曲张再破裂出血率。Objective To study the curative therapy of varices of esophagus and fundus of stomach.Methods 61 patients who needed flow-breaking of pericardial blood vessel we re divided r andomly into two groups.In control group(30 cases),traditional splenectomy plu s flow-breaking of pericardial vessel was performed.In observation group(31 ca s es),after splenectomy,flow-breaking of pericardial vessel was done close to w all of esophagus and stomach and collateral branch from coronary vein of stomach →paravenous plexus of esophagus→odd vein were kept clear.Biocholloid was used on wound surface for hemostasis and the lower part of esophagus and fundus of s tomach detached was covered with medical polyester flake.Results 3 and 5 years after operation,there were both significant differences (P<0.01,P <0.05,r espectively) in esophagus varices between the two groups.Recurrent rates of rup ture and hemorrhage of varices of esophagus and stomach fundus in observation gr oup were 6.5%(2/31)and 9.7%(3/31),respectively while those in Control group w ere 30% (9/30) and 53.3% (16/30).There were significant differences (P<0 .05 ,P<0.01,respectively) between the two groups,5 years after operation, death rates of recurrent rupture and hemorrhage of varices of esophagus and stomach f undus in observation group was 3.2% (1/31)while that in control group was 23. 3% (7/30),P<0.05.Conclusion Flow-breaking of pericardial blood vessel close to wall of stomach and esophagus combined with polyester flake covering may eff ectively stop establishment of new collateral circulation around esophagus and s tomach fundus,markedly reduce recurrent rate of rupture and hemorrhage of varic es of esophagus and stomach fundus after flow-breaking of pericardial vessel.
关 键 词:贲门周围血管离断术 食管胃底静脉曲张 涤纶片 食管壁 覆盖 食管静脉曲张程度 脾切除术后 胃冠状静脉 治疗方法 食管下段 破裂出血 侧支循环 对照组 观察组 出血率 再破裂 奇静脉 静脉丛 食管旁 胶止血 致死率 组分 相比
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