恶性血液病患者焦虑抑郁对免疫功能的影响及护理干预  

The investigation on the influence of the anxiety and depress of leukemia patients in autoimmunity

作　　者：余志华[1] 刘丛[1] 

机构地区：[1]深圳市第二人民医院护理部,518035

出　　处：《中国实用护理杂志》2005年第5期2-4,共3页Chinese Journal of Practical Nursing

基　　金：深圳市科技计划立项课题 (课题号 :2 0 0 2 0 40 86)

摘　　要：目的　探讨恶性血液病患者焦虑、抑郁状态及对免疫功能的影响,以便更好地为其提供护理干预。方法　应用汉密顿抑郁量表(HRSD)和汉密顿焦虑量表(HAMA) ,对恶性血液病患者和对照组健康人进行测评,应用免疫学检验技术和流式细胞仪检验技术,检测恶性血液病患者和对照组健康人的免疫功能。结果　与对照组比较,恶性血液病患者焦虑、抑郁程度差异有显著性(P <0 .0 1 ) ,恶性血液病患者焦虑、抑郁与自身免疫球蛋白IgA、IgG、IgM呈显著正相关。结论　恶性血液病患者焦虑、抑郁情绪可能与自身免疫功能有关。Objective To investigate the anxiety and depression of leukemia patients and influence for immunity function, in order to find a method of preventing. Methods Use HRSD and HAMA to investigate leukemia patients and health persons as a control group, check the immunity function of the patients and control group by laboratory and FCM. Results Compare with control group, the degree of anxiety and depress in leukemia patients are higher than that of control group. The difference between two groups is significant (P<0.01).The correlation between the degree anxiety and depression of patients and IgAIgGIgM is positive. Conclusion The anxiety and depress of leukemia patients may be relative with patients′ autoimmunity function.

关 键 词：恶性血液病患者 护理干预 焦虑抑郁 汉密顿焦虑量表 汉密顿抑郁量表 自身免疫功能 检验技术 流式细胞仪 免疫球蛋白 对照组 抑郁状态 抑郁情绪 健康人 免疫学 显著性 程度差 IgA IgG 正相关 IgM 

分 类 号：R473.73[医药卫生—护理学]