改良襻式胆肠内引流术与术后胆管炎关系的实验研究  

Experimental study on the relationships between postoperative cholangitis and modified biliary-enterostomy

作　　者：王小忠[1] 梁力建[2] 温思齐[1] 彭云恒[1] 廖文鹏[1] 洪伟勤[1] 谢锷[1] 

机构地区：[1]汕头市中心医院肝胆外科,广东汕头515031 [2]中山大学第一附属医院肝胆外科

出　　处：《中国基层医药》2005年第4期410-411,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　比较两种胆道内引流术与术后胆管炎的关系。方法　Begle犬16只,随机分为两组。改良组:改良襻式胆囊空肠吻合术;传统组:Roux en Y胆囊空肠吻合术。术后12周进行胆支肠襻细菌学检查和肝脏、胆囊、吻合口组织病理学检查。结果　离断空肠后的传统组胆支肠襻内存在着细菌容易增殖的内环境,术后胆支肠襻细菌的种类和数量特别是厌氧菌比改良组明显增加,术后胆管炎发生率也比改良组高。结论　不离断空肠的改良襻式胆管空肠吻合术可能减低术后胆管炎的发生率。Objective To select an optional biliary-enteric drainage based on the investigation of the relationships between postoperative cholangitis and two biliary-enteric drainage procedures.Methods 16 Begle's dogs were randomized to two groups.The conventional Roux-en-Y gallbladder-jejunum anastomosis group(conventional group,jejunum was transected).The modified gallbladder-jejunum loop anastomosis group(modified group,jejunum was not transected).Bacteriology of the biliary loop and the pathology of the liver,gallbladder and the anastomostic mouth were investigated after 12 weeks of surgery.Results The internal environment of biliary loop of the conventioal group favored bacteria growth for the transection of the jejunum.The bacterial flora and number of the biliary loop of the conventional group were significantly higher than those of the modified group,respectively.And subsequently,postoperative cholangitis episodes of the conventional group was more frequent than that of the modified group.Conclusion The modified gallbladder-jejunum loop anastomosis might decrease the occurrence of postoperative cholangitis.

关 键 词：改良襻式胆肠内引流术 术后 胆管炎 实验研究 

分 类 号：R657.4[医药卫生—外科学]