有机卤代反应中高效卤化试剂的应用及发展  

Application and Development of High Efficiency Halogenating Agents

作　　者：郑宾国[1] 李雪辉[1] 耿卫国[1] 张磊[1] 王乐夫[1] 

机构地区：[1]华南理工大学化学工程系,广州510640

出　　处：《天然气化工—C1化学与化工》2005年第2期70-74,共5页Natural Gas Chemical Industry

基　　金：广东省科技攻关项目(No .2 0 0 2B2 1 60 6;No . 2 0 3C3 3 50 3 );广东省自然科学基金(No .0 3 1 41 9)资助

摘　　要：卤代反应是有机合成中的一类重要反应,选择合适的卤化试剂是实现该类反应的关键,也是目前研究的热点之一。本文对近年来在高效卤化试剂研究方面取得的进展进行了综述,介绍了系列高效卤化剂在卤化取代反应、卤化加成反应等方面的应用。具体评述了不同卤化试剂的优缺点并展望了卤化试剂的发展趋势。Halogenating reaction is one of the most important reactions in organic synthesis and the choosing of appropriate halogenating reagent is the hot spot of this field and plays an important role in achieving this kind of reaction. In this paper, research progress in the studying of high efficiency halogenation agent in recent years was reviewed and the application of a series of high efficiency halogenating reagents in halogenating substitution reaction and halogenating addition reaction were introduced. The advantage and disadvantage of different halogenating agents were discussed and the developing tendency was prospected.

关 键 词：卤代反应 试剂 高效 应用 有机合成 取代反应 加成反应 发展趋势 卤化剂 优缺点 

分 类 号：O621.3[理学—有机化学] TQ455.42[理学—化学]