煤焦油瓷漆逸散物的致突变性研究  

Study on Mutagenicity of Coal Tar Enamel Volatiles

作　　者：姚加钦[1] 朱惠刚[1] 蒋颂辉[1] 宋伟民[1] 毛惠琴[1] 陈小琳[1] 张亚雄 陆章铿 张耀然 

机构地区：[1]上海医科大学环境卫生学教研室,上海海洋水下工程研究院

出　　处：《中国公共卫生学报》1994年第2期112-114,共3页

摘　　要：本文研究了煤焦油瓷漆逸散物（ＣＴＥＶ）的致突变性。结果表明ＣＴＥＶ能诱发碱基移码型突变，并且有一定的致染色体损伤作用。但小鼠分别在ＣＴＥＶ平均浓度为１８９、５４、１１ｍｇ／ｍ３空气中吸入染毒４ｈ２次．微核试验未出现阳性结果。The mutagenicity of Coal Tar Enamel Volatiles (CTEV)was studied. The results showed that CTEV could causebase-shift mutagenesis and chromosome damage,and therewas not positive result in mouse bone marrow micronucleustest when mice were exposued to average concentration 189,54,11mg/m3 of CTEV respectively for four hours twice.

关 键 词：煤焦油瓷漆 逸散物 致突变性 毒理 

分 类 号：R114[医药卫生—卫生毒理学]