Preparation and Cytotoxicity of Novel Aliphatic Polycarbonate Synthesized from Dihydroxyacetone  

作　　者：LianShengWANG XueSongJIANG HaoWANG SiXueCHENG RenXiZHUO 

机构地区：[1]KeyLaboratoryofBiomedicalPolymersofMinistryofEducation,DepartmentofChemistry,WuhanUniversity,Wuhan430072 [2]KeyLaboratoryofBiomedicalPolymersofMinistryofEducation,DepartmentofChemistry,WuhanUniversity,Wuhan430072／／DepartmentofChemistry,XiaoganUniversity,Xiaogan432000

出　　处：《Chinese Chemical Letters》2005年第5期572-574,共3页中国化学快报（英文版）

基　　金：This work was financially supported by The National Key Basic Research Program of China(G1999064703).

摘　　要：A new cyclic carbonate, 2,2-ethylenedioxypropane-1,3-diol carbonate (EOPDC), was synthesized through a two-step reaction from dihydroxyacetone dimer, and polymerized in bulk initiated by Sn(Oct)2 to give a high molecular weight polycarbonate. The structure of monomer and the polymer were characterized by FT-IR, 1H NMR, 13C NMR. The cytotoxicity of the obtained polycarbonate was investigated by MTT assay.

关 键 词：Ring-opening polymerization aliphatic polycarbonate cytotoxicity. 

分 类 号：O623.52[理学—有机化学] O633.14[理学—化学]