煅烧骨成骨效应实验研究  

Experimental study on forging bone in osteogeneticeffect

作　　者：宋进武 马贵骧[1] 贾佑民 周风泉 张根旺 

机构地区：[1]解放军二六三医院,北京市创伤骨科研究所

出　　处：《中国骨伤》1994年第1期10-11,共2页China Journal of Orthopaedics and Traumatology

摘　　要：作者采用取材丰富的家猪骨，经脱脂、脱蛋白、煅烧等工艺处理制成的煅烧骨（ＴｒｕｅｂｏｎｅＣｅｒａｍｉｃＴＢＣ）为植骨实验材料。将ＴＢＣ植入兔背肌肌囊、胫骨洞型骨膜骨缺损、桡骨骨干的骨膜骨缺损（２．５ｃｍ）内。术后２～１６周组织学观察表明：ＴＢＣ不引起组织排斥反应和炎症反应。ＴＢＣ网状孔隙内成骨活跃。荧光标记发现新生骨出现早、增加快、数量多。１６周ＴＢＣ与桡骨二断端愈合者１６／３０。Pig bone was developed into forging bone (true bone ceramic,TBC) through defatting,deproteinization and forging etc. techniques as experimental materal in bone transplantation. TBC were transplanted into capsule of rabbit back muscles, hole defect(2. 5cm) of tibial periosteal bone and radial shaft. The histological observation taken 2-16 weeks postoperatvely indicated that no excusive phenomenon and inflammatory reaction was found. There was active osteogenesis in the reticular formation of TBC. New born bone earlier,quicker and enormous was discovered by fluorescence labelling method. Sixteen within thirty cases were found healed between two fracture ends of TBC and radius after sixteen weeks.

关 键 词：煅烧骨 成骨效应 家猪 实验研究 

分 类 号：R687.34[医药卫生—骨科学]