若干大环铜(Ⅱ)、锰(Ⅱ)配合物模拟超氧化物歧化酶的研究  

Studies on simulation of SOD by some macrocyclic copper (Ⅱ) and manganese (Ⅱ) complexes

作　　者：梅光泉[1] 晏细元[2] 袁晓玲[2] 黄可龙[1] 

机构地区：[1]中南大学化学化工学院,湖南长沙410083 [2]宜春学院理学院,江西宜春336000

出　　处：《化学试剂》2005年第4期201-203,共3页Chemical Reagents

基　　金：江西省宜春市科技计划重点(20044718)资助项目江西省科协基金资助项目(20038803)。

摘　　要：用核黄素光照法测定了,8种大环铜(Ⅱ)、锰(Ⅱ)配合物的超氧化物歧化酶活性(SOD),结果表明,它们在1×10-4-1×10-7mol/L的浓度范围内均有50%以上抑制率,锰(Ⅱ)配合物表现出较铜(Ⅱ)配合物更低的SOD活性,对各模型化合物活性和结构的关系进行了探讨。By riboflavin illumination method, the SOD activity of eight macrocyclic copper (Ⅱ) and manganese (Ⅱ) complexes was measured. The relationship between the SOD activity and structure of model compounds was discussed. The results showed that all complexes had inhibition higher than 50 % in the concentration range of 10-to 10-7mol/L and manganese(Ⅱ) complexes had lower activity than copper(Ⅱ) complexes.

关 键 词：铜(Ⅱ)配合物 锰(Ⅱ)配合物 大环 超氧化物歧化酶 活性 

分 类 号：O643.361[理学—物理化学]