实验性声带麻痹神经吻合术后神经传导初步研究  

Experimental study of the neurophysiology of the lateral cricoarytenoid muscle a fter nervous reinnervation on the vocal cord paralysis in dogs

作　　者：何晓光[1] 孙俊[2] 张德芳[3] 于志成[4] 叶聪俊[1] 王文慧[1] 

机构地区：[1]昆明医学院附属第一医院耳鼻咽喉科,云南昆明650032 [2]昆明医学院解剖系,云南昆明650031 [3]昆明医学院附属第二医院肌电图室,云南昆明650101 [4]昆明医学院电生理室,云南昆明650031

出　　处：《中国耳鼻咽喉头颈外科》2005年第3期175-176,共2页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：云南省科技厅人才培养基金资助项目:(99C0028G)

摘　　要：目的研究喉返神经完全性损伤后颈袢神经支单纯支配环杓侧肌的电生理恢复情况。方法将实验组犬左喉返神经完全切断,3个月后,再将其内收肌支与同侧颈袢胸舌肌支延期吻合,吻合术后6个月检测环杓侧肌肌电活动情况。结果吻合术后6个月,左环杓侧肌可见肌电动作电位,其潜伏期为1.60±0.05ms,与术前相比较无显著差异,但神经传导速度为15.60±0.25m/s,较术前减慢,差异有显著性。结论喉返神经损伤后3月再行选择性环杓侧肌神经支配吻合术,能基本恢复肌肉电生理功能,但要达到完全正常水平,仍有待继续观察。OBJECTIVE To study the electro-neurogram of the lateral cricoaryten oid(LCA)muscle after nervous reinnervation on the vocal cord paralysis in dogs . METHODS The recurrent laryngeal nerve(RLN)of the left side was totally cut ,three months later,the adducent branch of the RLN was anastomosed with the bran ch of the cervical ansa . Six months after the reinnervation , the electro-neuro gram was examined to detect the function of the LCA. RESULTS Six months after t he operation,the nervous latency of LCA was 1.60 ± 0.05 ms,this showed no diffe rence with that of the normal LCA,but the nervous conduction speed of LCA was sl ower than that of the normal LCA. CONCLUSION The nervous reinnervation after t hree months of the vocal cord paralysis can recover the basic function of the la ryngeal muscle,but it still needs time to reach the total normal function .

关 键 词：术后 神经吻合 声带麻痹 步研究 实验性 环杓侧肌 神经传导速度 喉返神经损伤 完全性损伤 电生理功能 恢复情况 肌电活动 动作电位 神经支配 实验组 潜伏期 显著性 吻合术 颈袢 肌支 术前 

分 类 号：R767[医药卫生—耳鼻咽喉科]