原发性高血压患者心肌声学密度定量检测  

Quantitative assessment of myocardium in the patients with primary hypertension by acoustic densitometry

作　　者：曹礼庭[1] 高兴玉[2] 顾鹏[1] 张敏惠[1] 张青[1] 罗勇[2] 陈丽[2] 李健[3] 

机构地区：[1]四川省南充市川北医学院附院超声诊断科,四川南充637000 [2]四川省南充市川北医学院附院心内科,四川南充637000 [3]四川省南充市川北医学院附院统计学教研室,四川南充637000

出　　处：《中国医学影像技术》2005年第4期586-588,共3页Chinese Journal of Medical Imaging Technology

基　　金：四川省卫生厅科研项目(020029)。

摘　　要：目的　应用声学密度(AD)定量技术评价原发性高血压患者心肌损害程度。方法　用二维、M型超声检测正常人25例(对照组)、高血压心肌非肥厚患者26例(高血压1组)、高血压心肌肥厚患者30 例(高血压2 组)之室间隔、左室后壁舒张末期厚度及左室重量指数(LVMI);再用AD技术检测上述三组室间隔、左室后壁的AD参数即AII、AII%(室间隔与心包的AII的比值)及PPI值。结果　高血压2组之室间隔、左室后壁的厚度及LVMI分别高于高血压1组及对照组(P<0.05)。高血压2组之室间隔、左室后壁的AII%、PPI分别高于高血压1 组及对照组(P<0.05)。左室壁的厚度与其相应部位的AII%、左室重量指数与室间隔、左室后壁的AII%均存在中度相关性。结论　AD定量技术可作为评价原发性高血压患者心肌损害极其程度的参考指标。Objective To assess severity of myocardial damage in patients with primary hypertension (PH) by acoustic densitometry (AD) quantitative technology. Methods The thickness of interventricular septum (IVS) and left ventricular posterior wall (LVPW) at end diastolic and left ventricular mass index (LVMI) in normal group ( n =25), PH nonhypertrophy group ( n =26), PH hypertrophy group ( n =30) were measured by M-mode and Two-dimensional echocardiography respectively. The parameters of average image intensity (AII), AII% (normalized AII) and peak to peak intensity (PPI) in IVS, LVPW of 3 groups mentioned above were measured by AD technology. Results The thickness of IVS,LVPW and LVMI in PH hypertrophy group was higher than that of the normal group, nonhypertrophy group respectively ( P <0.05). AII%, PPI of IVS, LVPW in hypertrophy group were higher than those of the normal group and nonhypertrophy group respectively ( P <0.05). The moderate correlations were found between the thickness of ventricular wall and its AII%, between LVMI and AII% of IVS, LVPW. Conclusion AD quantitative technology can be used as referential index to assess severity of myocardial damage in the patients with primary hypertension.

关 键 词：高血压 心肌 声学密度 超声检查 

分 类 号：R544.1[医药卫生—心血管疾病] R445.2[医药卫生—内科学]