益气活血法治疗多发性梗死性痴呆30例临床研究  

Clinical Study on the Method for Supplementing Qi and Activating Blood Circulation for Treatment of 30 Cases of Multiple Infarctional Dementia

作　　者：吴晓红[1] 

机构地区：[1]江苏省无锡市中医医院神经内科,无锡市后西溪33号214001

出　　处：《中医杂志》2005年第4期267-269,共3页Journal of Traditional Chinese Medicine

摘　　要：目的:观察消栓益智胶囊对多发性梗死性痴呆(MID)的临床疗效。方法:将符合中西医诊断标准的50例 MID 患者随机分为消栓益智胶囊治疗组与喜得镇对照组,分别观察症状,长谷川痴呆量表(HDS)、简易智能量表(MMSE)积分,血脂,血液流变学,红细胞超氧化物歧化酶(SOD),血浆过氧化脂质(LPO)。结果:消栓益智胶囊治疗 MID 的总有效率达90%,该药不仅能改善症状,提高 HDS、MMSE 积分,而且能调节血脂,降低血流变指标,改善 SOD、LPO。结论:消栓益智胶囊疗效优于喜得镇。Objective:To observe clinical therapeutic effect of Xiaoshuan Yizhi Capsules on multiple infarctional dementia(MID).Methods:50 cases of MID were randomly divided into Xiaoshuan Yizhi Capsules treatment group and Hydergine control group.Their symptoms and signs,cumulative scores of Haseguwa's Dementia Scale(HDS)and Mini-mental state examination(MMSE),blood lipids,hemorheologic indexes,superoxide dismutase(SOD)activity in red cells,plasma lipids of peroxide(LPO)content were investigated. Results:The total effective rate was 90% in the treatment group,and Xiaoshuan Yizhi Capsules not only improved symptoms and signes,increased cumulative scores of HDS and MMSE,and also regulated blood lipids,decreased hemorheologic indexes,raised SOD activity and decreased LPO content.Conclusion:Xiaoshuan Yizhi Capsule is superior to Hydergine in treatment of MID.

关 键 词：多发性梗死性痴呆 益气活血法治疗 临床研究 超氧化物歧化酶(SOD) 长谷川痴呆量表 血浆过氧化脂质 益智胶囊 简易智能量表 血液流变学 血流变指标 临床疗效 诊断标准 总有效率 MMSE 调节血脂 喜得镇 MID 消栓 对照组 治疗组 

分 类 号：R277.7[医药卫生—中医学]