囊虫性脑脓肿内虫体的观察  

DIFFERENT FORMS OF CYSTICERCUS CELLULOSAE HARBORED IN CYSTICERCOTIC BRAIN ABSCESSES FROM PATIENTS

作　　者：孟宪钦[1] 王松山[1] 吴玉锦 

机构地区：[1]河北医学院寄生虫学教研室,河北省医院神经外科

出　　处：《中国寄生虫病防治杂志》1994年第4期270-273,共4页Chinese Journal of Parasitic Disease Control

摘　　要：手术摘除单发脑实质小型脓肿５０例，作光镜、部分作电镜观察。共检出活虫５例，死虫４３例，未发现囊虫组织者２例。４３例死虫中１６例尚具有完整或不完整的囊壁（３７．２％），１３例仅为囊虫残体（３０．２％），１４例囊虫已完全崩解（３２．６％）。４８例囊虫多位于灰质或灰白质相间处。其中顶部２７例、额部１０例、枕部５例、额部５例及基底神经节处１例。电镜观察活虫无明显改变，但有的虫体出现体表破溃及表皮剥脱现象。频死虫体体表损害明显，微毛脱落严重，表皮层及实质层均有较大的空泡变性，肌层疏松、断裂，实质层呈空网状，网管内充以少量解体的组织颗粒。死亡虫体结构不清，多呈电镜低密度状态，微毛仅留少许或完全脱失，皮层解体，呈均匀一致的颗粒状，肌层紊乱、肿胀，有头钩溶解现象，产生聚集的钩体蛋白。死虫组织退化严重时，体表完全脱失，实质层广泛剥脱，可见一些破碎的实质细胞及肌肉碎片，但是，保留下来的石灰小体多数完整无损、结构清晰；死虫组织进一步退化则虫体完全破坏、崩解，呈残体状。在脑脓肿内最后消失的囊虫组织成分是石灰小体，该小体因数量多、形态恒定，光镜或电镜下均可找到，是１个可靠的诊断依据，特别适用于鉴定瓦解型囊虫。本研究的５０例脑脓肿中４?ifty patients with the single form ofsmall hrain abscess were surgically treated.The removed abscesses were examinedhistopathologically under light microscope,scanning electron aud transmission electronmicroscope for tbe presence and status of cys-ticercus.It was found that the brain abscessesin 48 cases were caused by Cysticercus cellu-losae,5 surviving and 43 dead worms.Therewas no trace of cysticercus infection in theotber 2 cases.Forty-eight cysticerci showedvarying degrees of degeneration : surviving,nearly dying or dead at the point of completedisintegration,The calcareous corpuscles inthe tissue of the dead larvae which would dis-appeare from the brain abscess at last , espe-cially those larvae of being disintegrated ordissolved also could serve as the diagnostic in-dication for cysticercotic brain ahscesses.Inall our 48 cases the corpuscles were observed.

关 键 词：猪囊尾蚴 囊尾蚴病 脑脓肿 超微结构 

分 类 号：R532.330.3[医药卫生—内科学] R742.703[医药卫生—临床医学]