支气管哮喘患儿血清吸入性过敏原特异性IgE研究  

Study on serum aeroallergen specific IgE in children with bronchial asthma

作　　者：赵萍[1] 孔玲玲[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院儿科,430022

出　　处：《中国妇幼保健》2005年第9期1090-1091,共2页Maternal and Child Health Care of China

摘　　要：目的:了解吸入性过敏原在儿童哮喘中的临床意义。方法:采用酶联免疫吸附试孔检测147例患儿血清总IgE和屋尘、尘螨、霉菌、豚草花粉、树花粉等6组常见吸入性过敏原特异性IgE。结果:儿童哮喘组总IgE和特异性IgE阳性率均最高,每组患儿6种过敏原中以屋尘和螨虫阳性率最高。结论:儿童哮喘组对吸入性过敏原呈高度致敏状态,而婴儿哮喘组阳性检测率较低可能与年龄和所接触的环境有关,每组过敏原的高低对支气管哮喘的治疗和预后有重要的临床意义和指导作用。Objective:To investigate the clinical role of aeroallergen in bronchial asthma in children.Methods:The total serum IgE and serum specific IgE of house dust, dermatophagoides, mixed molds, ragweed, mugwort and trees pollens were detected by ELISA in 147 cases of children.Results:The positive rate of serum total IgE and specific IgE was the highest in children asthma group. Of 6 kinds of allergens, the positive rate of house dust and dermatophagoides was the highest in each group.Conclusion:The children in asthma group were more sensitive to aeroallergens, but infants with lower sensitivity to aeroallergens could be related to age and surrounding. The allergen levels in each group could play an important clinical significance and guidance role in treatment and prognosis of bronchial asthma of children.

关 键 词：儿童哮喘 吸入性过敏原 特异性IGE 

分 类 号：R725.6[医药卫生—儿科]