紫外分光光度法测定抗乳腺增生乳膏中达那唑的含量  

Content Determination of Danazol in the Anti-hyperplasia of Mammary Glands Cream by UV Spec-trophotometry

作　　者：黄建敏[1] 付小菊[1] 黄翠珍[1] 

机构地区：[1]珠海市人民医院,珠海市519000

出　　处：《中国药房》2005年第9期701-702,共2页China Pharmacy

摘　　要：目的建立抗乳腺增生乳膏中达那唑的含量测定方法。方法采用紫外分光光度法,测定波长为285nm。结果达那唑检测浓度在5～25μg/ml范围内线性关系良好(r=0.9999),平均回收率为99.2%(RSD=0.32%,n=5)。结论本方法简便、快速、准确,可用于该制剂的含量测定与质量控制。OBJECTIVE:To establish a method for the assaying of danazol in anti-hyperplasia of mammary glands cream.METHODS:The UV-spectrophometry was adopted to determine the content of dianozol with the wavelength at285nm.RESULTS:The dianzol was in linear relationship within the concentration range of5～25μg/ml(r=0.9999).The average recovery rate was99.2%(RSD=0.32%,n=5).CONCLUSION:The method is simple,rapid and accurate,which is suitable for the content determination and quality control of the preparation.

关 键 词：紫外分光光度法 抗乳腺增生乳膏 达那唑 含量 

分 类 号：R927.2[医药卫生—药学]