高乌甲素、咪唑安定超前镇痛镇静在腹部手术前的应用  

Application of lappaconitine and midazolam preemptive analgesia and calm before abdominal operation

作　　者：夏晓琼[1] 赵兵[1] 郭春年[1] 

机构地区：[1]安徽省巢湖市第一人民医院麻醉科,安徽巢湖238000

出　　处：《安徽医药》2005年第5期336-337,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的观察高乌甲素和咪啶安定在腹部手术前超前镇痛镇静的效应。方法选择50例腹部手术病人,ASAⅠ～Ⅱ级,随机分为两组,试验组为高乌甲素1.6mg·kg-1+咪唑安定0.04mg·kg-1+阿托品0.01mg·kg-1,对照组为安定0.2mg·kg-1+阿托品0.01mg·kg-1,观察两组术中警觉/镇静评分(OAA/S)及添加辅助用药的人次。结果试验组肌内注射10min后,OAA/S下降为4.0±0.5,30min后为3.4±0.52,而对照组分别为4.9±0.2和4.3±0.54,两组相比(P<0.05),而术中辅助用药,试验组为6例(占24%),对照组为22例(占88%),两者相比P<0.01。结论术前使用高乌甲素和咪唑安定起到超前镇痛、镇静的效果。Aim To observe the effects of lappaconitine and midazolam preemptive analgesia and calm before abdominal operation. Methods 50 patients of abdominal operation were divided into two groups randomly. Test group: lappaconitine 1.6 mg·kg - 1+midazolam 0.04 mg·kg - 1+Atropin 0.01 mg·kg - 1, Contrast group:valium 0.2 mg·kg - 1+Atropin 0.01 mg·kg - 1. The OAA/S and assist medicine of two group were observed during operation. Results The test group: The OAA/S were 4.0±0.5 and 3.4±0.52 in 10 min, 30 min respectively. The contrast group: The OAA/S were 4.9±0.2 and 4.3±0.54(P<0.05).The test group: the assist medicine was 6 patients(24%).The contrast group: the assist medicine was 22 patients(88%),P<0.01. Conclusion Lappaconitive and midazolam have the effects of preemptive analgesia and clam before operation application.

关 键 词：高乌甲素 超前镇痛 咪唑安定 手术前 警觉/镇静评分 腹部手术病人 术中辅助用药 咪啶安定 肌内注射 阿托品 对照组 ASA 试验 相比 

分 类 号：R614[医药卫生—麻醉学] R614.42[医药卫生—外科学]