包结物晶析法选择分离辛夷挥发油中1,8-桉叶素  

Selective Isolation of 1,8-Cineole from Volatile Oil of Flos Magnoliae(Xin Yi) via Inclusion Crystalline

作　　者：郭文生[1] 郭放[1] 佟健[1] 常键 蔡云平 刘成雁 侯冬岩[3] 回瑞华[3] 

机构地区：[1]辽宁大学化学科学与工程学院,沈阳110036 [2]辽宁省分析测试研究中心,沈阳110015 [3]鞍山师范学院化学系,鞍山114005

出　　处：《高等学校化学学报》2005年第5期883-885,F012,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20372031);沈阳市科技局自然科学基金资助.

摘　　要：We used 1,1,6,6-tetraphenylhexa-2,4-diyne-1,6-diol（A） as the host molecule to selectively recognize the component 1,8-cineole（B） in the volatile oil of Flos Magnoliae（Xin Yi）. The inclusion compound（A+B） was formed as crystalline, and the structure was confirmed by means of IR, （（）1H NMR）, and single crystal X-ray diffraction, with the 1∶2 molar ratios of the host to the guest. The component 1,8-cineole（B） was selectively isolated from the inclusion compound（A+B） by Kugelrohr vaccum technology, and then further characterized by IR, （）1H NMR and （）13C NMR. The whole components in the volatile oil of Flos Magnoliae（Xin Yi） and the isolation effect of 1,8-cineole isolated from inclusion crystals were analyzed by GC and GC-MS, respectively. The result indicate that the good isolation effect is given by the inclusion method, with purity and yield of the component 1,8-cineole（B） separated from the volatile oil of Flos Magnoliae are 100% and 85%, respectively.We used 1,1,6,6-tetraphenylhexa-2,4-diyne-1,6-diol(A) as the host molecule to selectively recognize the component 1,8-cineole(B) in the volatile oil of Flos Magnoliae(Xin Yi). The inclusion compound(A+B) was formed as crystalline, and the structure was confirmed by means of IR, (()~1H NMR), and single crystal X-ray diffraction, with the 1∶2 molar ratios of the host to the guest. The component 1,8-cineole(B) was selectively isolated from the inclusion compound(A+B) by Kugelrohr vaccum technology, and then further characterized by IR, ()~1H NMR and ()^(13)C NMR. The whole components in the volatile oil of Flos Magnoliae(Xin Yi) and the isolation effect of 1,8-cineole isolated from inclusion crystals were analyzed by GC and GC-MS, respectively. The result indicate that the good isolation effect is given by the inclusion method, with purity and yield of the component 1,8-cineole(B) separated from the volatile oil of Flos Magnoliae are 100% and 85%, respectively.

关 键 词：分子识别 包结化合物 辛夷挥发油 1 8-桉叶素 分离 

分 类 号：O626[理学—有机化学]