pH及温度敏感性N-异丙基丙烯酰胺-丙烯酸共聚微凝胶的制备与表征(英文)  

Preparation and characterization of pH and temperature sensitive poly(N-isopropylacrylamide-co-acrylic acid) microgel

作　　者：李亚娜[1] 霍东霞[1] 钱庆文[2] 刘玉坤[1] 

机构地区：[1]郑州大学材料工程学院,河南郑州450052 [2]郑州大学第一附属医院,河南郑州450052

出　　处：《合成橡胶工业》2005年第3期222-222,共1页China Synthetic Rubber Industry

基　　金：SupportedbyNaturalScienceFoundationofHenanEducationDepartment(2001430019)

摘　　要：通过无皂乳液聚合得到了N-异丙基丙烯酰胺和丙烯酸的无规共聚物微凝胶,用电导仪测定了该微凝胶的表面羧基含量,用分光光度计测定了水凝胶溶液透光率在不同pH值和温度条件下的变化。结果表明,该微凝胶表面羧基含量随着聚合反应中丙烯酸质量分数的增加而增大;微凝胶表面羧基含量直接影响微凝胶的环境敏感性。Microgel is widely applied due to its upstanding characters such as better biocompatibility, biodegradation, low toxicity and sensitive to physical and chemical microenvironment.In this work,a group of pH-temperature sensitive crosslinked poly( N -isopropylacrylamide-co-acrylic acid) (PNIPAM/AAc) microgels were synthesized by surfactant-free emulsion polymerization. The reaction was carried out with N,N′ -methylenebis(acrylamide) crosslinking agent and K 2S 4O 8 as initiator.The amounts of surface —COOH of microgel particles were measured.When the mass fraction of AAc was 0,5%,10%,15%, the amount of surface —COOH of microgel particles was 0.242 1,1.062 3,1.813 8 mmol/g,respectively. The results indicated that the amount of surface —COOH of microgel particles increased with the mass fraction of AAc. The prepared microgel suspensions were dried on a plate at room temperature,and then analyzed by atom force micro-scopy.

关 键 词：N-异丙基丙烯酰胺 微凝胶 丙烯酸 制备与表征 温度敏感性 无皂乳液聚合 羧基含量 无规共聚物 分光光度计 温度条件 质量分数 聚合反应 直接影响 表面 电导仪 pH值 透光率 水凝胶 测定 

分 类 号：TQ427.6[化学工程]