有机磷杀虫剂对致倦库蚊群体抗性相关酯酶的选择作用  

Status of Esterase B of Culex quinquefasciatus in Field Population from China under Organophosphorus Insecticide Selection Pressure

作　　者：徐建农[1] 瞿逢伊[1] 刘维德[1] 

机构地区：[1]第二军医大学寄生虫学教研室,中国科学院上海昆虫研究所

出　　处：《中国媒介生物学及控制杂志》1994年第4期241-243,共3页Chinese Journal of Vector Biology and Control

摘　　要：广东佛山有机磷抗性致倦库蚊群体中有８种高活性酯酶Ｂ（ＥＢ），本实验用两种ＯＰ杀虫剂（马拉硫磷和倍硫磷）处理现场蚊虫，观察存活个体酯酶类型的变化，发现耐受９５％致死剂量的马拉硫磷个体只带有ＥＢ１，而耐受９６％致死剂量倍硫磷的个体表现３种ＥＢ，但ＥＢ１比例上升，说明３种ＥＢ对不同的ＯＰ有不同的选择优势，ＥＢ１的抗性效率较高。讨论了多种ＯＰ压力对抗性相关酯酶产生的影响。Electrophoretic analysis of mosquitoes of Culex quinquefasciatus sampled in 1992 from Foshan, China, revealed 3 highly active esterases(EB1, EB2 and EB3). These esterases are involved in organophosphate resistance. After treatment the population by 95% lethal dose of malathion,all surviving mosquitoes possessed only EB1 phenotype,but 96% lethal dose of fenthion did not select special estcrase, 3 phenotypes were present in survivors, although the proportion of EB1 increased. The results indicate that EB1 is more efficient in providing OP resistance than EB2 and EB3,and various esterases have different selective advantage under different OP pressures.

关 键 词：致倦库蚊 有机磷 杀虫剂 抗性 酯酶 

分 类 号：R184.31[医药卫生—流行病学]